Obesity and the gut microbiome: Striving for causality

Por Harley, Isaac T.W., Karp, Christopher L.
Publicado em 2012

Genetic Susceptibility to Lupus: New Insights from fine mapping and genome-wide association studies

Por Harley, Isaac T.W., Kaufman, Kenneth M., Langefeld, Carl D., Harley, John B., Kelly, Jennifer A.
Publicado em 2009

MDM2 Polymorphism Increases Susceptibility to Childhood Acute Myeloid Leukemia: A Report from the Children’s Oncology Group

Por Phillips, Christine L, Gerbing, Robert, Alonzo, Todd, Perentesis, John P, Harley, Isaac TW, Meshinchi, Soheil, Bhatla, Deepika, Radloff, Gretchen, Davies, Stella M
Publicado em 2010

The Effect of Inversion at 8p23 on BLK Association with Lupus in Caucasian Population

Por Namjou, Bahram, Ni, Yizhao, Harley, Isaac T. W., Chepelev, Iouri, Cobb, Beth, Kottyan, Leah C., Gaffney, Patrick M., Guthridge, Joel M., Kaufman, Kenneth, Harley, John B.
Publicado no PLoS One (2014)

Prolidase deficiency breaks tolerance to lupus-associated antigens

Por Dsouza, Anil, Kurien, Biji T., Bruner, Benjamin F., Gross, Timothy, James, Judith A, Targoff, Ira N., Maier-Moore, Jacen S., Harley, Isaac T.W., Wang, Heng, Scofield, R. Hal
Publicado em 2013

Distinct Tlr4-expressing cell compartments control neutrophilic and eosinophilic airway inflammation

Por McAlees, Jaclyn W., Whitehead, Gregory S., Harley, Isaac T.W., Cappelletti, Monica, Rewerts, Cheryl L., Holdcroft, A. Maria, Divanovic, Senad, Wills-Karp, Marsha, Finkelman, Fred D., Karp, Christopher L., Cook, Donald N.
Publicado no Mucosal Immunol (2014)

IL-17 Signaling Accelerates the Progression of Nonalcoholic Fatty Liver Disease in Mice

Por Harley, Isaac TW, Stankiewicz, Traci E, Giles, Daniel A, Softic, Samir, Flick, Leah M, Cappelletti, Monica, Sheridan, Rachel, Xanthakos, Stavra A, Steinbrecher, Kris A, Sartor, R Balfour, Kohli, Rohit, Karp, Christopher L, Divanovic, Senad
Publicado em 2014

Osteopontin and Systemic Lupus Erythematosus Association: A Probable Gene-Gender Interaction

Por Han, Shizhong, Guthridge, Joel M., Harley, Isaac T. W., Sestak, Andrea L., Kim-Howard, Xana, Kaufman, Kenneth M., Namjou, Bahram, Deshmukh, Harshal, Bruner, Gail, Espinoza, Luis R., Gilkeson, Gary S., Harley, John B., James, Judith A., Nath, Swapan K.
Publicado em 2008

Differential colonization with segmented filamentous bacteria and Lactobacillus murinus do not drive divergent development of diet-induced obesity in C57BL/6 mice

Por Harley, Isaac T.W., Giles, Daniel A., Pfluger, Paul T., Burgess, Stacey L., Walters, Stephanie, Hembree, Jazzminn, Raver, Christine, Rewerts, Cheryl L., Downey, Jordan, Flick, Leah M., Stankiewicz, Traci E., McAlees, Jaclyn W., Wills-Karp, Marsha, Balfour Sartor, R., Divanovic, Senad, Tschöp, Matthias H., Karp, Christopher L.
Publicado em 2013

Type I interferons regulate susceptibility to inflammation-induced preterm birth

Por Cappelletti, Monica, Presicce, Pietro, Lawson, Matthew J., Chaturvedi, Vandana, Stankiewicz, Traci E., Vanoni, Simone, Harley, Isaac T.W., McAlees, Jaclyn W., Giles, Daniel A., Moreno-Fernandez, Maria E., Rueda, Cesar M., Senthamaraikannan, Paranth, Sun, Xiaofei, Karns, Rebekah, Hoebe, Kasper, Janssen, Edith M., Karp, Christopher L., Hildeman, David A., Hogan, Simon P., Kallapur, Suhas G., Chougnet, Claire A., Way, Sing Sing, Divanovic, Senad
Publicado no JCI Insight (2017)

IFRD1 polymorphisms in cystic fibrosis with potential link to altered neutrophil function

Por Gu, YuanYuan, Harley, Isaac T. W., Henderson, Lindsay B., Aronow, Bruce J., Vietor, Ilja, Huber, Lukas A., Harley, John B., Kilpatrick, Jeffrey R., Langefeld, Carl D., Williams, Adrienne H., Jegga, Anil G., Chen, Jing, Wills-Karp, Marsha, Arshad, S. Hasan, Ewart, Susan L., Thio, Chloe L., Flick, Leah M., Filippi, Marie-Dominique, Grimes, H. Leighton, Drumm, Mitchell L., Cutting, Garry R., Knowles, Michael R., Karp, Christopher L.
Publicado em 2009

Identification of ATPAF1 as a novel candidate gene for asthma in children

Por Schauberger, Eric M., Ewart, Susan L., Arshad, Syed H., Huebner, Marianne, Karmaus, Wilfried, Holloway, John W., Friderici, Karen H., Ziegler, Julie T., Zhang, Hongmei, Rose-Zerilli, Mathew J., Barton, Sheila J., Holgate, Stephen T., Kilpatrick, Jeffrey R., Harley, John B., Lajoie-Kadoch, Stephane, Harley, Isaac T. W., Hamid, Qutayba, Kurukulaaratchy, Ramesh J., Seibold, Max A., Avila, Pedro C., Rodriguez-Citron, William, Rodriguez-Santana, Jose R., Hu, Donglei, Gignoux, Christopher, Romieu, Isabelle, London, Stephanie J., Burchard, Esteban G., Langefeld, Carl D., Wills-Karp, Marsha
Publicado em 2011

The Role of Genetic Variation Near Interferon-Kappa in Systemic Lupus Erythematosus

Por Harley, Isaac T. W., Niewold, Timothy B., Stormont, Rebecca M., Kaufman, Kenneth M., Glenn, Stuart B., Franek, Beverly S., Kelly, Jennifer A., Kilpatrick, Jeffrey R., Hutchings, David, Divers, Jasmin, Bruner, Gail R., Edberg, Jeffrey C., McGwin, Gerald, Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá-Pérez, Luis M., Merrill, Joan T., Gilkeson, Gary S., Vyse, Timothy J., Alarcón-Riquelme, Marta E., Cho, Soo-Kyung, Jacob, Chaim O., Alarcón, Graciela S., Moser, Kathy L., Gaffney, Patrick M., Kimberly, Robert P., Bae, Sang-Cheol, Langefeld, Carl D., Harley, John B., Guthridge, Joel M., James, Judith A.
Publicado em 2010

Genetic Associations of LYN with Systemic Lupus Erythematosus

Por Lu, Rufei, Vidal, Gabriel S., Kelly, Jennifer A, Delgado-Vega, Angélica M, Kim-Howard, Xana, Macwana, Susan R, Dominguez, Nicolas, Klein, Wendy, Burrell, Christian, Harley, Isaac T, Kaufman, Kenneth M, Bruner, Gail R, Moser, Kathy L, Gaffney, Patrick M, Gilkeson, Gary S, Wakeland, Edward K, Li, Quan-Zhen, Langefeld, Carl D, Marion, Miranda C, Divers, Jasmin, Alarcón, Graciela S, Brown, Elizabeth E, Kimberly, Robert P, Edberg, Jeffery C, Ramsey-Goldman, Rosalind, Reveille, John D, McGwin, Gerald, Vilá, Luis M, Petri, Michelle A, Bae, Sang-Cheol, Cho, Soo-Kyung, Bang, So-Young, Kim, IL, Choi, Chan-Bum, Martin, Javier, Vyse, Timothy J, Merrill, Joan T, Harley, John B, Alarcón-Riquelme, Marta E, Nath, Swapan K, James, Judith A, Guthridge, Joel M
Publicado em 2009

Evaluation of TRAF6 in a Large Multi-Ancestral Lupus Cohort

Por Namjou, Bahram, Choi, Chan-Bum, Harley, Isaac T. W., Alarcón-Riquelme, Marta E., Kelly, Jennifer A., Glenn, Stuart B., Ojwang, Joshua O., Adler, Adam, Kim, Kwangwoo, Gallant, Caroline J., Boackle, Susan A., Criswell, Lindsey A., Kimberly, Robert P., Brown, Elizabeth E., Edberg, Jeffrey, Alarcón, Graciela S., Stevens, Anne M., Jacob, Chaim O., Gilkeson, Gary S., Kamen, Diane L., Tsao, Betty P., Anaya, Juan-Manuel, Kim, Eun-Mi, Park, So-Yeon, Sung, Yoon-Kyoung, Guthridge, Joel M., Merrill, Joan T., Petri, Michelle, Ramsey-Goldman, Rosalind, Vilá, Luis M., Niewold, Timothy B., Martin, Javier, Pons-Estel, Bernardo A., Vyse, Timothy J., Freedman, Barry I., Moser, Kathy L., Gaffney, Patrick M., Williams, Adrienne H., Comeau, Mary E., Reveille, John D., Kang, Changwon, James, Judith A., Scofield, R. Hal, Langefeld, Carl D., Kaufman, Kenneth M., Harley, John B., Bae, Sang-Cheol
Publicado em 2012

Lupus risk variants in the PXK locus alter B-cell receptor internalization

Por Vaughn, Samuel E., Foley, Corinne, Lu, Xiaoming, Patel, Zubin H., Zoller, Erin E., Magnusen, Albert F., Williams, Adrienne H., Ziegler, Julie T., Comeau, Mary E., Marion, Miranda C., Glenn, Stuart B., Adler, Adam, Shen, Nan, Nath, Swapan, Stevens, Anne M., Freedman, Barry I., Tsao, Betty P., Jacob, Chaim O., Kamen, Diane L., Brown, Elizabeth E., Gilkeson, Gary S., Alarcón, Graciela S., Reveille, John D., Anaya, Juan-Manuel, James, Judith A., Moser, Kathy L., Criswell, Lindsey A., Vilá, Luis M., Alarcón-Riquelme, Marta E., Petri, Michelle, Scofield, R. Hal, Kimberly, Robert P., Ramsey-Goldman, Rosalind, Binjoo, Young, Choi, Jeongim, Bae, Sang-Cheol, Boackle, Susan A., Vyse, Timothy J., Guthridge, Joel M., Namjou, Bahram, Gaffney, Patrick M., Langefeld, Carl D., Kaufman, Kenneth M., Kelly, Jennifer A., Harley, Isaac T. W., Harley, John B., Kottyan, Leah C.
Publicado no Front Genet (2015)

Two Functional Lupus-Associated BLK Promoter Variants Control Cell-Type- and Developmental-Stage-Specific Transcription

Por Guthridge, Joel M., Lu, Rufei, Sun, Harry, Sun, Celi, Wiley, Graham B., Dominguez, Nicolas, Macwana, Susan R., Lessard, Christopher J., Kim-Howard, Xana, Cobb, Beth L., Kaufman, Kenneth M., Kelly, Jennifer A., Langefeld, Carl D., Adler, Adam J., Harley, Isaac T.W., Merrill, Joan T., Gilkeson, Gary S., Kamen, Diane L., Niewold, Timothy B., Brown, Elizabeth E., Edberg, Jeffery C., Petri, Michelle A., Ramsey-Goldman, Rosalind, Reveille, John D., Vilá, Luis M., Kimberly, Robert P., Freedman, Barry I., Stevens, Anne M., Boackle, Susan A., Criswell, Lindsey A., Vyse, Tim J., Behrens, Timothy W., Jacob, Chaim O., Alarcón-Riquelme, Marta E., Sivils, Kathy L., Choi, Jiyoung, Joo, Young Bin, Bang, So-Young, Lee, Hye-Soon, Bae, Sang-Cheol, Shen, Nan, Qian, Xiaoxia, Tsao, Betty P., Scofield, R. Hal, Harley, John B., Webb, Carol F., Wakeland, Edward K., James, Judith A., Nath, Swapan K., Graham, Robert R., Gaffney, Patrick M.
Publicado em 2014