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Prolidase deficiency breaks tolerance to lupus-associated antigens

BACKGROUND: Prolidase deficiency is a rare autosomal recessive disease in which one of the last steps of collagen metabolism, cleavage of proline-containing dipeptides, is impaired. Only about 93 patients have been reported with about 10% also having systemic lupus erythematosus (SLE). METHODS: We s...

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Detalhes bibliográficos
Main Authors: Dsouza, Anil, Kurien, Biji T., Bruner, Benjamin F., Gross, Timothy, James, Judith A, Targoff, Ira N., Maier-Moore, Jacen S., Harley, Isaac T.W., Wang, Heng, Scofield, R. Hal
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4030668/
https://ncbi.nlm.nih.gov/pubmed/24330273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/1756-185X.12254
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