Development of bestatin-based activity-based probes for metallo-aminopeptidases

Por Harbut, Michael B., Velmourougane, Geetha, Reiss, Gilana, Chandramohanadas, Rajesh, Greenbaum, Doron C.
Publicado em 2008

Replication bypass of N(2)-deoxyguanosine interstrand cross-links by human DNA polymerases η and ι

Por Klug, Alex R., Harbut, Michael B., Lloyd, R. Stephen, Minko, Irina G.
Publicado em 2012

Replication Bypass of Interstrand Cross-link Intermediates by Escherichia coli DNA Polymerase IV

Por Kumari, Anuradha, Minko, Irina G., Harbut, Michael B., Finkel, Steven E., Goodman, Myron F., Lloyd, R. Stephen
Publicado em 2008

Synthesis of new (-)-Bestatin-based inhibitor libraries reveals a novel binding mode in the S1 pocket of the essential malaria M1 metalloaminopeptidase

Por Velmourougane, Geetha, Harbut, Michael B., Dalal, Seema, McGowan, Sheena, Oellig, Christine A., Meinhardt, Nataline, Whisstock, James C., Klemba, Michael, Greenbaum, Doron C.
Publicado em 2011

Bestatin-based chemical biology strategy reveals distinct roles for malaria M1- and M17-family aminopeptidases

Por Harbut, Michael B., Velmourougane, Geetha, Dalal, Seema, Reiss, Gilana, Whisstock, James C., Onder, Ozlem, Brisson, Dustin, McGowan, Sheena, Klemba, Michael, Greenbaum, Doron C.
Publicado em 2011

Apicomplexan Parasites Co-Opt Host Calpains to Facilitate Their Escape from Infected Cells

Por Chandramohanadas, Rajesh, Davis, Paul H., Beiting, Daniel P., Harbut, Michael B., Darling, Claire, Velmourougane, Geetha, Lee, Ming Yeh, Greer, Peter A., Roos, David S., Greenbaum, Doron C.
Publicado em 2009

Auranofin exerts broad-spectrum bactericidal activities by targeting thiol-redox homeostasis

Por Harbut, Michael B., Vilchèze, Catherine, Luo, Xiaozhou, Hensler, Mary E., Guo, Hui, Yang, Baiyuan, Chatterjee, Arnab K., Nizet, Victor, Jacobs, William R., Schultz, Peter G., Wang, Feng
Publicado no Proc Natl Acad Sci U S A (2015)

Role for DNA Polymerase κ in the Processing of N(2)-N(2)-Guanine Interstrand Cross-links

Por Minko, Irina G., Harbut, Michael B., Kozekov, Ivan D., Kozekova, Albena, Jakobs, Petra M., Olson, Susan B., Moses, Robb E., Harris, Thomas M., Rizzo, Carmelo J., Lloyd, R. Stephen
Publicado em 2008

Targeting the ERAD pathway via inhibition of signal peptide peptidase for antiparasitic therapeutic design

Por Harbut, Michael B., Patel, Bhumit A., Yeung, Bryan K. S., McNamara, Case W., Bright, A. Taylor, Ballard, Jaime, Supek, Frantisek, Golde, Todd E., Winzeler, Elizabeth A., Diagana, Thierry T., Greenbaum, Doron C.
Publicado em 2012

Determinants of the Inhibition of DprE1 and CYP2C9 by Antitubercular Thiophenes

Por Liu, Renhe, Lyu, Xiaoxuan, Batt, Sarah M, Hsu, Mei‐Hui, Harbut, Michael B, Vilchèze, Catherine, Cheng, Bo, Ajayi, Kehinde, Yang, Baiyuan, Yang, Yun, Guo, Hui, Lin, Changyou, Gan, Fei, Wang, Chen, Franzblau, Scott G., Jacobs, William R., Besra, Gurdyal S., Johnson, Eric F., Petrassi, Mike, Chatterjee, Arnab K., Fütterer, Klaus, Wang, Feng
Publicado no Angew Chem Int Ed Engl (2017)