Evaluation of a novel CD20-targeted IL-15 immunotherapeutic with potent activity against B cell lymphoma

af Liu, Bai, Kong, Lin, Marcus, Warren D, Chen, Xiaoyue, Han, Kaiping, Rhode, Peter R, Wong, Hing C
Udgivet i J Immunother Cancer (2014)

Combination therapy of an IL-15 superagonist complex, ALT-803, and a tumor targeting monoclonal antibody promotes direct antitumor activity and protective vaccinal effect in a syng...

af Chen, Xiaoyue, Liu, Bai, Han, Kaiping, Kong, Lin, Noel, Terra, Jeng, Emily K, Alter, Sarah, Rubinstein, Mark, Rhode, Peter R, Wong, Hing C
Udgivet i J Immunother Cancer (2015)

Novel Human Interleukin-15 Agonists

af Zhu, Xiaoyun, Marcus, Warren D., Xu, Wenxin, Lee, Hyung-Il, Han, Kaiping, Egan, Jack O., Yovandich, Jason L., Rhode, Peter R., Wong, Hing C.
Udgivet 2009

Novel antitumor mechanism-of-action of an IL-2 fusion protein mediated by tumor associated macrophage repolarization and innate-like CD8+ memory T cells

af Xu, Wenxin, Egan, Jack O, Liu, Bai, Chen, Xiaoyue, You, Lijing, Han, Kaiping, Marcus, Warren D, Kong, Lin, Jones, Monica, Jeng, Emily K, Rhode, Peter R, Wong, Hing C
Udgivet i J Immunother Cancer (2014)

Efficacy and Mechanism-of-Action of a Novel Superagonist Interleukin-15: Interleukin-15 Receptor α/Fc Fusion Complex in Syngeneic Murine Models of Multiple Myeloma

af Xu, Wenxin, Jones, Monica, Liu, Bai, Zhu, Xiaoyun, Johnson, C. Bryce, Edwards, Ana C., Kong, Lin, Jeng, Emily K., Han, Kaiping, Marcus, Warren D., Rubinstein, Mark P., Rhode, Peter R., Wong, Hing C.
Udgivet 2013

A Novel Fusion of ALT-803 (Interleukin (IL)-15 Superagonist) with an Antibody Demonstrates Antigen-specific Antitumor Responses

af Liu, Bai, Kong, Lin, Han, Kaiping, Hong, Hao, Marcus, Warren D., Chen, Xiaoyue, Jeng, Emily K., Alter, Sarah, Zhu, Xiaoyun, Rubinstein, Mark P., Shi, Sixiang, Rhode, Peter R., Cai, Weibo, Wong, Hing C.
Udgivet i J Biol Chem (2016)

Comparison of the super agonist complex, ALT-803, to IL-15 as cancer immunotherapeutics in animal models

af Rhode, Peter R., Egan, Jack O., Xu, Wenxin, Hong, Hao, Webb, Gabriela M., Chen, Xiaoyue, Liu, Bai, Zhu, Xiaoyun, Wen, Jinghai, You, Lijing, Kong, Lin, Edwards, Ana C., Han, Kaiping, Shi, Sixiang, Alter, Sarah, Sacha, Jonah B., Jeng, Emily K., Cai, Weibo, Wong, Hing C.
Udgivet i Cancer Immunol Res (2015)

The IL-15-based ALT-803 complex enhances FcγRIIIa-triggered NK cell responses and in vivo clearance of B cell lymphomas

af Rosario, Maximillian, Bai, Liu, Kong, Lin, Collins, Lynne I., Schneider, Stephanie E., Chen, Xiaoyue, Han, Kaiping, Jeng, Emily K., Rhode, Peter R., Leong, Jeffrey W., Schappe, Timothy, Jewell, Brea A., Keppel, Catherine R., Shah, Keval, Hess, Brian, Romee, Rizwan, Piwnica-Worms, David R., Cashen, Amanda F., Bartlett, Nancy L., Wong, Hing C., Fehniger, Todd A.
Udgivet i Clin Cancer Res (2015)