The path from mitochondrial ROS to aging runs through the mitochondrial permeability transition pore

Por Rottenberg, Hagai, Hoek, Jan B.
Publicado no Aging Cell (2017)

Alcohol and epigenetic regulation: Do the products of alcohol metabolism drive epigenetic control of gene expression in alcohol-related disorders?

Por Vadigepalli, Rajanikanth, Hoek, Jan B.
Publicado no Alcohol Clin Exp Res (2018)

Epidemiology of Moderate Alcohol Consumption and Breast Cancer: Association or Causation?

Por Zakhari, Samir, Hoek, Jan B.
Publicado no Cancers (Basel) (2018)

Regulation of Hexokinase Binding to VDAC

Por Pastorino, John G., Hoek, Jan B.
Publicado em 2008

Computational modeling analysis of mitochondrial superoxide production under varying substrate conditions and upon inhibition of different segments of the electron transport chain

Por Markevich, Nikolai I., Hoek, Jan B.
Publicado no Biochim Biophys Acta (2015)

Temporal and functional profile of the transcriptional regulatory network in the early regenerative response to partial hepatectomy in the rat

Por Juskeviciute, Egle, Vadigepalli, Rajanikanth, Hoek, Jan B
Publicado em 2008

Alcohol and Mitochondria: A Dysfunctional Relationship

Por HOEK, JAN B., CAHILL, ALAN, PASTORINO, JOHN G.
Publicado em 2002

Signaling switches and bistability arising from multisite phosphorylation in protein kinase cascades

Por Markevich, Nick I., Hoek, Jan B., Kholodenko, Boris N.
Publicado em 2004

Multi-strip Western blotting to increase quantitative data output

Por Aksamitiene, Edita, Hoek, Jan B., Kholodenko, Boris, Kiyatkin, Anatoly
Publicado em 2007

ADENINE NUCLEOTIDE CHANGES IN THE REMNANT LIVER: AN EARLY SIGNAL FOR REGENERATION AFTER PARTIAL HEPATECTOMY*

Por Crumm, Sara, Cofan, Montserrat, Juskeviciute, Egle, Hoek, Jan B.
Publicado em 2008

Advancing Alcohol Biomarkers Research

Por Bearer, Cynthia F., Bailey, Shannon M., Hoek, Jan B.
Publicado em 2010

Novel Comparative Pattern Count Analysis Reveals a Chronic Ethanol-Induced Dynamic Shift in Immediate Early NF-κB Genome-wide Promoter Binding During Liver Regeneration

Por Kuttippurathu, Lakshmi, Patra, Biswanath, Hoek, Jan B, Vadigepalli, Rajanikanth
Publicado no Mol Biosyst (2016)

Chronic Ethanol Consumption Causes Alterations in the Structural Integrity of Mitochondrial DNA in Aged Rats

Por Cahill, Alan, Stabley, Gabriel J., Wang, Xiaolan, Hoek, Jan B.
Publicado em 1999

Pharmacological ceramide reduction alleviates alcohol-induced steatosis and hepatomegaly in adiponectin knockout mice

Por Correnti, Jason M., Juskeviciute, Egle, Swarup, Aditi, Hoek, Jan B.
Publicado em 2014

Chronic ethanol feeding enhances miR-21 induction during liver regeneration while inhibiting proliferation in rats

Por Dippold, Rachael P., Vadigepalli, Rajanikanth, Gonye, Gregory E., Hoek, Jan B.
Publicado em 2012

In Vivo Zonal Variation and Liver Cell-Type Specific NF-κB Localization after Chronic Adaptation to Ethanol and following Partial Hepatectomy

Por Nilakantan, Harshavardhan, Kuttippurathu, Lakshmi, Parrish, Austin, Hoek, Jan B., Vadigepalli, Rajanikanth
Publicado no PLoS One (2015)

Pattern analysis uncovers a chronic ethanol-induced disruption of the switch-like dynamics of C/EBP-β and C/EBP-α genome-wide binding during liver regeneration

Por Kuttippurathu, Lakshmi, Patra, Biswanath, Cook, Daniel, Hoek, Jan B., Vadigepalli, Rajanikanth
Publicado no Physiol Genomics (2017)

Signaling through Receptors and Scaffolds: Independent Interactions Reduce Combinatorial Complexity

Por Borisov, Nikolay M., Markevich, Nick I., Hoek, Jan B., Kholodenko, Boris N.
Publicado em 2005

Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains.

Por Borisov, Nikolay M., Markevich, Nick I., Hoek, Jan B., Kholodenko, Boris N.
Publicado em 2005

Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades

Por Markevich, Nick I, Tsyganov, Mikhail A, Hoek, Jan B, Kholodenko, Boris N
Publicado em 2006