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Chronic Ethanol Consumption Causes Alterations in the Structural Integrity of Mitochondrial DNA in Aged Rats

Chronic ethanol consumption adversely affects the respiratory activity of rat liver mitochondria. It causes increased cellular production of oxygen radical species and selectively decreases mitochondrial glutathione (GSH) levels. Here we show, using Southern hybridization techniques on total rat gen...

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Detalhes bibliográficos
Main Authors: Cahill, Alan, Stabley, Gabriel J., Wang, Xiaolan, Hoek, Jan B.
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2647744/
https://ncbi.nlm.nih.gov/pubmed/10498638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.510300434
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