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A Ca(2+)-induced mitochondrial permeability transition causes complete release of rat liver endonuclease G activity from its exclusive location within the mitochondrial intermembrane space. Identification of a novel endo-exonuclease activity residing within the mitochondrial matrix

Endonuclease G, a protein historically thought to be involved in mitochondrial DNA (mtDNA) replication, repair, recombination and degradation, has recently been reported to be involved in nuclear DNA degradation during the apoptotic process. As a result, its involvement in mtDNA homeostasis has been...

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Библиографические подробности
Главные авторы: Davies, Adrian M., Hershman, Stuart, Stabley, Gabriel J., Hoek, Jan B., Peterson, Jason, Cahill, Alan
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2003
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC150224/
https://ncbi.nlm.nih.gov/pubmed/12582256
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