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Chronic Ethanol Consumption Increases Myocardial Mitochondrial DNA Mutations: A Potential Contribution by Mitochondrial Topoisomerases

Aims: Alcoholic cardiomyopathy (ACM) presents as decreased myocardial contractility, arrhythmias and secondary non-ischemic dilated cardiomyopathy leading to heart failure. Mitochondrial dysfunction is known to have a significant role in the development and complications of ACM. This study investiga...

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Detalhes bibliográficos
Main Authors: Laurent, D., Mathew, J.E., Mitry, M., Taft, M., Force, A., Edwards, J.G.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060737/
https://ncbi.nlm.nih.gov/pubmed/24852753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/alcalc/agu029
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