EXTH-60. PLK1 INHIBITOR TARGETS MISMATCH REPAIR DEFICIENT TEMOZOLOMIDE RESISTANT GLIOMA

Por Higuchi, Fumi, Cahill, Daniel, Wakimoto, Hiroaki
Publicado no Neuro Oncol (2017)

DRES-16. PARP INHIBITORS RESTORE TEMOZOLOMIDE SENSITIVITY IN MSH6-DEFICIENT TEMOZOLOMIDE-RESISTANT GLIOMA MODELS

Por Higuchi, Fumi, Wakimoto, Hiroaki, Cahill, Daniel
Publicado no Neuro Oncol (2017)

CN-19 HISTOLOGICAL EXAMINATION OF ENHANCING LESION ADJACENT TO THE IMPLANTED BCNU- WAFERS SUGGESTS VASCULAR DAMAGE AS THE MAJOR UNDERLYING MECHANISM

Por Ueki, Keisuke, Matsuda, Hadzki, Higuchi, Fumi, Udzuka, Takeo, Kim, Phyo
Publicado em 2014

GENETIC AND HISTOLOGICAL STABILITY OF OLIGODENDROGLIAL TUMORS WITH 1P/19Q CO-DELETION EVEN AFTER CHEMOTHERAPY AND OR RADIATION THERAPY

Por Ueki, Keisuke, Aihara, Koki, Mukasa, Akitake, Higuchi, Fumi, Matsuda, Hazki, Kim, Phyo
Publicado em 2014

Metastasis to the Choroid Plexus from Thyroid Cancer: Case Report

Por Kitagawa, Yosuke, Higuchi, Fumi, Abe, Yoshihiro, Matsuda, Hadzuki, Kim, Phyo, Ueki, Keisuke
Publicado no Neurol Med Chir (Tokyo) (2013)

NIMG-68 (11)C-METHIONIN-PET ENABLES EARLY DETECTION AND SUBSEQUENT INTERVENTION OF RECURRENCE IN 1p/19q CO-DELETED GLIOMAS

Por Ueki, Keisuke, Higuchi, Fumi, Ohtani, Ryohei, Udzuka, Takeshi, Sakamoto, Setsu, Kim, Phyo
Publicado no Neuro Oncol (2015)

Intravascular Lymphoma with an Acute Course of Cerebellar Hemorrhage: A Case Report

Por UZUKA, Takeo, HIGUCHI, Fumi, MATSUDA, Hadzuki, OTANI, Ryohei, KIM, Phyo, UEKI, Keisuke
Publicado no Neurol Med Chir (Tokyo) (2018)

PATH-21. IDH-MUTATED, 19q DELETED, TP53 MUTATED ANAPLASTIC GLIOMAS CONSTITUTE A SUBGROUP THAT LOOK LIKE AND BEHAVE LIKE ANAPLASTIC OLIGODENDROGLIOMAS

Por Otani, Ryohei, Uzuka, Takeo, Higuchi, Fumi, Matsuda, Hazuki, Tanaka, Shota, Mukasa, Akitake, Ichimura, Kohichi, Kim, Phyo, Ueki, Keisuke
Publicado no Neuro Oncol (2017)

IDH‐mutated astrocytomas with 19q‐loss constitute a subgroup that confers better prognosis

Por Otani, Ryohei, Uzuka, Takeo, Higuchi, Fumi, Matsuda, Hadzki, Nomura, Masashi, Tanaka, Shota, Mukasa, Akitake, Ichimura, Koichi, Kim, Phyo, Ueki, Keisuke
Publicado no Cancer Sci (2018)

EXTH-14. THE ALKYLATING CHEMOTHERAPEUTIC TEMOZOLOMIDE INDUCES METABOLIC STRESS AND POTENTIATES NAD+ DEPLETION-MEDIATED CELL DEATH IN IDH1 MUTANT CANCERS

Por Tateishi, Kensuke, Miller, Julie, Higuchi, Fumi, Koerner, Mara V A, Lelic, Nina, Curry, William, Batchelor, Tracy, Wakimoto, Hiroaki, Chi, Andrew S, Cahill, Daniel
Publicado no Neuro Oncol (2017)

A nationwide multi-institutional retrospective study to identify prognostic factors and develop a graded prognostic assessment system for patients with brain metastases from uterin...

Por Hayashi, Nakamasa, Takahashi, Hideaki, Hasegawa, Yuzo, Higuchi, Fumi, Takahashi, Masamichi, Makino, Keishi, Takagaki, Masatoshi, Akimoto, Jiro, Okuda, Takeshi, Okita, Yoshiko, Mitsuya, Koichi, Hirashima, Yasuyuki, Narita, Yoshitaka, Nakasu, Yoko
Publicado no BMC Cancer (2017)

The alkylating chemotherapeutic temozolomide induces metabolic stress in IDH1-mutant cancers and potentiates NAD+ depletion-mediated cytotoxicity

Por Tateishi, Kensuke, Higuchi, Fumi, Miller, Julie J., Koerner, Mara V.A., Lelic, Nina, Shankar, Ganesh M., Tanaka, Shota, Fisher, David E., Batchelor, Tracy T., Iafrate, A. John, Wakimoto, Hiroaki, Chi, Andrew S., Cahill, Daniel P.
Publicado no Cancer Res (2017)

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma

Por Braun, Christian J., Stanciu, Monica, Boutz, Paul L., Patterson, Jesse C., Calligaris, David, Higuchi, Fumi, Neupane, Rachit, Fenoglio, Silvia, Cahill, Daniel P., Wakimoto, Hiroaki, Agar, Nathalie Y. R., Yaffe, Michael B., Sharp, Phillip A., Hemann, Michael T., Lees, Jacqueline A.
Publicado no Cancer Cell (2017)

A Multicenter Phase I/II Study of the BCNU Implant (Gliadel (®) Wafer) for Japanese Patients with Malignant Gliomas

Por AOKI, Tomokazu, NISHIKAWA, Ryo, SUGIYAMA, Kazuhiko, NONOGUCHI, Naosuke, KAWABATA, Noriyuki, MISHIMA, Kazuhiko, ADACHI, Jun-ichi, KURISU, Kaoru, YAMASAKI, Fumiyuki, TOMINAGA, Teiji, KUMABE, Toshihiro, UEKI, Keisuke, HIGUCHI, Fumi, YAMAMOTO, Tetsuya, ISHIKAWA, Eiichi, TAKESHIMA, Hideo, YAMASHITA, Shinji, ARITA, Kazunori, HIRANO, Hirofumi, YAMADA, Shinobu, MATSUTANI, Masao
Publicado no Neurol Med Chir (Tokyo) (2014)

A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas

Por Arita, Hideyuki, Yamasaki, Kai, Matsushita, Yuko, Nakamura, Taishi, Shimokawa, Asanao, Takami, Hirokazu, Tanaka, Shota, Mukasa, Akitake, Shirahata, Mitsuaki, Shimizu, Saki, Suzuki, Kaori, Saito, Kuniaki, Kobayashi, Keiichi, Higuchi, Fumi, Uzuka, Takeo, Otani, Ryohei, Tamura, Kaoru, Sumita, Kazutaka, Ohno, Makoto, Miyakita, Yasuji, Kagawa, Naoki, Hashimoto, Naoya, Hatae, Ryusuke, Yoshimoto, Koji, Shinojima, Naoki, Nakamura, Hideo, Kanemura, Yonehiro, Okita, Yoshiko, Kinoshita, Manabu, Ishibashi, Kenichi, Shofuda, Tomoko, Kodama, Yoshinori, Mori, Kanji, Tomogane, Yusuke, Fukai, Junya, Fujita, Koji, Terakawa, Yuzo, Tsuyuguchi, Naohiro, Moriuchi, Shusuke, Nonaka, Masahiro, Suzuki, Hiroyoshi, Shibuya, Makoto, Maehara, Taketoshi, Saito, Nobuhito, Nagane, Motoo, Kawahara, Nobutaka, Ueki, Keisuke, Yoshimine, Toshiki, Miyaoka, Etsuo, Nishikawa, Ryo, Komori, Takashi, Narita, Yoshitaka, Ichimura, Koichi
Publicado no Acta Neuropathol Commun (2016)