A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas

The prognostic impact of TERT mutations has been controversial in IDH-wild tumors, particularly in glioblastomas (GBM). The controversy may be attributable to presence of potential confounding factors such as MGMT methylation status or patients’ treatment. This study aimed to evaluate the impact of...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Arita, Hideyuki, Yamasaki, Kai, Matsushita, Yuko, Nakamura, Taishi, Shimokawa, Asanao, Takami, Hirokazu, Tanaka, Shota, Mukasa, Akitake, Shirahata, Mitsuaki, Shimizu, Saki, Suzuki, Kaori, Saito, Kuniaki, Kobayashi, Keiichi, Higuchi, Fumi, Uzuka, Takeo, Otani, Ryohei, Tamura, Kaoru, Sumita, Kazutaka, Ohno, Makoto, Miyakita, Yasuji, Kagawa, Naoki, Hashimoto, Naoya, Hatae, Ryusuke, Yoshimoto, Koji, Shinojima, Naoki, Nakamura, Hideo, Kanemura, Yonehiro, Okita, Yoshiko, Kinoshita, Manabu, Ishibashi, Kenichi, Shofuda, Tomoko, Kodama, Yoshinori, Mori, Kanji, Tomogane, Yusuke, Fukai, Junya, Fujita, Koji, Terakawa, Yuzo, Tsuyuguchi, Naohiro, Moriuchi, Shusuke, Nonaka, Masahiro, Suzuki, Hiroyoshi, Shibuya, Makoto, Maehara, Taketoshi, Saito, Nobuhito, Nagane, Motoo, Kawahara, Nobutaka, Ueki, Keisuke, Yoshimine, Toshiki, Miyaoka, Etsuo, Nishikawa, Ryo, Komori, Takashi, Narita, Yoshitaka, Ichimura, Koichi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977715/
https://ncbi.nlm.nih.gov/pubmed/27503138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0351-2
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