A combination of TERT promoter mutation and MGMT methylation status predicts clinically relevant subgroups of newly diagnosed glioblastomas

The prognostic impact of TERT mutations has been controversial in IDH-wild tumors, particularly in glioblastomas (GBM). The controversy may be attributable to presence of potential confounding factors such as MGMT methylation status or patients’ treatment. This study aimed to evaluate the impact of...

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Zapisane w:
Opis bibliograficzny
Wydane w:Acta Neuropathol Commun
Główni autorzy: Arita, Hideyuki, Yamasaki, Kai, Matsushita, Yuko, Nakamura, Taishi, Shimokawa, Asanao, Takami, Hirokazu, Tanaka, Shota, Mukasa, Akitake, Shirahata, Mitsuaki, Shimizu, Saki, Suzuki, Kaori, Saito, Kuniaki, Kobayashi, Keiichi, Higuchi, Fumi, Uzuka, Takeo, Otani, Ryohei, Tamura, Kaoru, Sumita, Kazutaka, Ohno, Makoto, Miyakita, Yasuji, Kagawa, Naoki, Hashimoto, Naoya, Hatae, Ryusuke, Yoshimoto, Koji, Shinojima, Naoki, Nakamura, Hideo, Kanemura, Yonehiro, Okita, Yoshiko, Kinoshita, Manabu, Ishibashi, Kenichi, Shofuda, Tomoko, Kodama, Yoshinori, Mori, Kanji, Tomogane, Yusuke, Fukai, Junya, Fujita, Koji, Terakawa, Yuzo, Tsuyuguchi, Naohiro, Moriuchi, Shusuke, Nonaka, Masahiro, Suzuki, Hiroyoshi, Shibuya, Makoto, Maehara, Taketoshi, Saito, Nobuhito, Nagane, Motoo, Kawahara, Nobutaka, Ueki, Keisuke, Yoshimine, Toshiki, Miyaoka, Etsuo, Nishikawa, Ryo, Komori, Takashi, Narita, Yoshitaka, Ichimura, Koichi
Format: Artigo
Język:Inglês
Wydane: BioMed Central 2016
Hasła przedmiotowe:
Research
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977715/
https://ncbi.nlm.nih.gov/pubmed/27503138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0351-2
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