The roles of prostaglandin F(2) in regulating the expression of matrix metalloproteinase-12 via an insulin growth factor-2-dependent mechanism in sheared chondrocytes

por Guan, Pei-Pei, Ding, Wei-Yan, Wang, Pu
Publicado no Signal Transduct Target Ther (2018)

Elevating the Levels of Calcium Ions Exacerbate Alzheimer’s Disease via Inducing the Production and Aggregation of β-Amyloid Protein and Phosphorylated Tau

por Guan, Pei-Pei, Cao, Long-Long, Wang, Pu
Publicado no Int J Mol Sci (2021)

Cyclooxygenase-2 is critical for the propagation of β-amyloid protein and reducing the glycosylation of tau in Alzheimer’s disease

por Guan, Pei-Pei, Yu, Xin, Zou, Yan-Hui, Wang, Pu
Publicado no Cell Mol Immunol (2019)

Cyclooxygenase-2 Induced the β-Amyloid Protein Deposition and Neuronal Apoptosis Via Upregulating the Synthesis of Prostaglandin E(2) and 15-Deoxy-Δ(12,14)-prostaglandin J(2)

por Guan, Pei-Pei, Liang, Yun-Yue, Cao, Long-Long, Yu, Xin, Wang, Pu
Publicado no Neurotherapeutics (2019)

Fluid shear stress-induced osteoarthritis: roles of cyclooxygenase-2 and its metabolic products in inducing the expression of proinflammatory cytokines and matrix metalloproteinase...

por Wang, Pu, Guan, Pei-Pei, Guo, Chuang, Zhu, Fei, Konstantopoulos, Konstantinos, Wang, Zhan-You
Publicado em 2013

Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1

por Cao, Long-Long, Guan, Pei-Pei, Liang, Yun-Yue, Huang, Xue-Shi, Wang, Pu
Publicado no Front Aging Neurosci (2019)

Prostaglandin A1 Inhibits the Cognitive Decline of APP/PS1 Transgenic Mice via PPARγ/ABCA1-dependent Cholesterol Efflux Mechanisms

por Xu, Guo-Biao, Yang, Liu-Qing, Guan, Pei-Pei, Wang, Zhan-You, Wang, Pu
Publicado no Neurotherapeutics (2019)

Rofecoxib Attenuates the Pathogenesis of Amyotrophic Lateral Sclerosis by Alleviating Cyclooxygenase-2-Mediated Mechanisms

por Zou, Yan-Hui, Guan, Pei-Pei, Zhang, Shen-Qing, Guo, Yan-Su, Wang, Pu
Publicado no Front Neurosci (2020)

Aggravation of Alzheimer’s disease due to the COX-2-mediated reciprocal regulation of IL-1β and Aβ between glial and neuron cells

por Wang, Pu, Guan, Pei-Pei, Wang, Tao, Yu, Xin, Guo, Jian-Jun, Wang, Zhan-You
Publicado no Aging Cell (2014)

Prostaglandin I(2) Attenuates Prostaglandin E(2)-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism

por Wang, Pu, Guan, Pei-Pei, Yu, Xin, Zhang, Li-Chao, Su, Ya-Nan, Wang, Zhan-You
Publicado no Sci Rep (2016)

Magnesium Ions Inhibit the Expression of Tumor Necrosis Factor α and the Activity of γ-Secretase in a β-Amyloid Protein-Dependent Mechanism in APP/PS1 Transgenic Mice

por Yu, Xin, Guan, Pei-Pei, Zhu, Di, Liang, Yun-Yue, Wang, Tao, Wang, Zhan-You, Wang, Pu
Publicado no Front Mol Neurosci (2018)

Transferrin is responsible for mediating the effects of iron ions on the regulation of anterior pharynx-defective-1α/β and Presenilin 1 expression via PGE(2) and PGD(2) at the earl...

por Lu, Chen-Di, Ma, Ji-Kang, Luo, Zheng-Yang, Tai, Qun-Xi, Wang, Pu, Guan, Pei-Pei
Publicado no Aging (Albany NY) (2018)

COX-2 metabolic products, the prostaglandin I(2) and F(2α), mediate the effects of TNF-α and Zn(2+) in stimulating the phosphorylation of Tau

por Wang, Yue, Guan, Pei-Pei, Yu, Xin, Guo, Yan-Su, Zhang, Ying-Jie, Wang, Zhan-You, Wang, Pu
Publicado no Oncotarget (2017)

The Role of Cyclooxygenase-2, Interleukin-1β and Fibroblast Growth Factor-2 in the Activation of Matrix Metalloproteinase-1 in Sheared-Chondrocytes and Articular Cartilage

por Guan, Pei-Pei, Guo, Jing-Wen, Yu, Xin, Wang, Yue, Wang, Tao, Konstantopoulos, Konstantinos, Wang, Zhan-You, Wang, Pu
Publicado no Sci Rep (2015)

Magnesium ion influx reduces neuroinflammation in Aβ precursor protein/Presenilin 1 transgenic mice by suppressing the expression of interleukin-1β

por Wang, Pu, Yu, Xin, Guan, Pei-Pei, Guo, Jing-Wen, Wang, Yue, Zhang, Yan, Zhao, Hang, Wang, Zhan-You
Publicado no Cell Mol Immunol (2017)

Influences of Sodium Carbonate on Physicochemical Properties of Lansoprazole in Designed Multiple Coating Pellets

por He, Wei, Yang, Min, Fan, Jun Hong, Feng, Cai Xia, Zhang, Su Juan, Wang, Jin Xu, Guan, Pei Pei, Wu, Wei
Publicado em 2010

Prostaglandin I(2) upregulates the expression of anterior pharynx‐defective‐1α and anterior pharynx‐defective‐1β in amyloid precursor protein/presenilin 1 transgenic mice

por Wang, Pu, Guan, Pei‐Pei, Guo, Jing‐Wen, Cao, Long‐Long, Xu, Guo‐Biao, Yu, Xin, Wang, Yue, Wang, Zhan‐You
Publicado no Aging Cell (2016)

By activating matrix metalloproteinase-7, shear stress promotes chondrosarcoma cell motility, invasion and lung colonization

por Guan, Pei-Pei, Yu, Xin, Guo, Jian-Jun, Wang, Yue, Wang, Tao, Li, Jia-Yi, Konstantopoulos, Konstantinos, Wang, Zhan-You, Wang, Pu
Publicado no Oncotarget (2015)