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Prostaglandin I(2) upregulates the expression of anterior pharynx‐defective‐1α and anterior pharynx‐defective‐1β in amyloid precursor protein/presenilin 1 transgenic mice

Cyclooxygenase‐2 (COX‐2) has been recently identified to be involved in the pathogenesis of Alzheimer's disease (AD). Yet, the role of an important COX‐2 metabolic product, prostaglandin (PG) I(2), in the pathogenesis of AD remains unknown. Using human‐ and mouse‐derived neuronal cells as well...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Aging Cell
Hauptverfasser: Wang, Pu, Guan, Pei‐Pei, Guo, Jing‐Wen, Cao, Long‐Long, Xu, Guo‐Biao, Yu, Xin, Wang, Yue, Wang, Zhan‐You
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013024/
https://ncbi.nlm.nih.gov/pubmed/27240539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12495
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