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Prostaglandin I(2) upregulates the expression of anterior pharynx‐defective‐1α and anterior pharynx‐defective‐1β in amyloid precursor protein/presenilin 1 transgenic mice

Cyclooxygenase‐2 (COX‐2) has been recently identified to be involved in the pathogenesis of Alzheimer's disease (AD). Yet, the role of an important COX‐2 metabolic product, prostaglandin (PG) I(2), in the pathogenesis of AD remains unknown. Using human‐ and mouse‐derived neuronal cells as well...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Wang, Pu, Guan, Pei‐Pei, Guo, Jing‐Wen, Cao, Long‐Long, Xu, Guo‐Biao, Yu, Xin, Wang, Yue, Wang, Zhan‐You
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5013024/
https://ncbi.nlm.nih.gov/pubmed/27240539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12495
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