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Prostaglandin I(2) Attenuates Prostaglandin E(2)-Stimulated Expression of Interferon γ in a β-Amyloid Protein- and NF-κB-Dependent Mechanism
Cyclooxygenase-2 (COX-2) has been recently identified as being involved in the pathogenesis of Alzheimer’s disease (AD). However, the role of an important COX-2 metabolic product, prostaglandin (PG) I(2), in AD development remains unknown. Using mouse-derived astrocytes as well as APP/PS1 transgenic...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4751455/ https://ncbi.nlm.nih.gov/pubmed/26869183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20879 |
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