Insights on how the Mycobacterium tuberculosis heme uptake pathway can be used as a drug target

Por Owens, Cedric P, Chim, Nicholas, Goulding, Celia W
Publicado em 2013

Insights into redox sensing metalloproteins in Mycobacterium tuberculosis

Por Chim, Nicholas, Johnson, Parker M., Goulding, Celia W.
Publicado em 2013

Heme uptake in bacterial pathogens

Por Contreras, Heidi, Chim, Nicholas, Credali, Alfredo, Goulding, Celia W.
Publicado em 2014

Introducing the new bacterial branch of the RNase A superfamily

Por Cuthbert, Bonnie J., Burley, Kalistyn H., Goulding, Celia W.
Publicado no RNA Biol (2017)

Unusual diheme conformation of the heme degrading protein from Mycobacterium tuberculosis

Por Chim, Nicholas, Iniguez, Angelina, Nguyen, Tran Que, Goulding, Celia W.
Publicado em 2009

Advances in Mycobacterium tuberculosis therapeutics discovery utlizing structural biology

Por Chim, Nicholas, Owens, Cedric P., Contreras, Heidi, Goulding, Celia W.
Publicado em 2012

Structures of Oligomers of a Peptide from β-Amyloid

Por Pham, Johnny D., Chim, Nicholas, Goulding, Celia W., Nowick, James S.
Publicado em 2013

Characterization of heme ligation properties of Rv0203, a secreted heme binding protein involved in Mycobacterium tuberculosis heme uptake

Por Owens, Cedric P., Du, Jing, Dawson, John H., Goulding, Celia W.
Publicado em 2012

The Near-iron Transporter (NEAT) Domains of the Anthrax Hemophore IsdX2 Require a Critical Glutamine to Extract Heme from Methemoglobin

Por Honsa, Erin S., Owens, Cedric P., Goulding, Celia W., Maresso, Anthony W.
Publicado em 2013

Structural and biochemical characterization of the essential DsbA-like disulfide bond forming protein from Mycobacterium tuberculosis

Por Chim, Nicholas, Harmston, Christine A, Guzman, David J, Goulding, Celia W
Publicado em 2013

Structural snapshots along the reaction pathway of Yersinia pestis RipA, a putative butyryl-CoA transferase

Por Torres, Rodrigo, Lan, Benson, Latif, Yama, Chim, Nicholas, Goulding, Celia W.
Publicado em 2014

A New Way to Degrade Heme: THE MYCOBACTERIUM TUBERCULOSIS ENZYME MhuD CATALYZES HEME DEGRADATION WITHOUT GENERATING CO

Por Nambu, Shusuke, Matsui, Toshitaka, Goulding, Celia W., Takahashi, Satoshi, Ikeda-Saito, Masao
Publicado em 2013

Structural insights into RipC, a putative citrate lyase β subunit from a Yersinia pestis virulence operon

Por Torres, Rodrigo, Chim, Nicholas, Sankaran, Banumathi, Pujol, Céline, Bliska, James B., Goulding, Celia W.
Publicado em 2011

Heme degradation by Staphylococcus aureus IsdG and IsdI liberates formaldehyde rather than carbon monoxide

Por Matsui, Toshitaka, Nambu, Shusuke, Ono, Yukari, Goulding, Celia W., Tsumoto, Kouhei, Ikeda-Saito, Masao
Publicado em 2013

Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation

Por Matsui, Toshitaka, Nambu, Shusuke, Goulding, Celia W., Takahashi, Satoshi, Fujii, Hiroshi, Ikeda-Saito, Masao
Publicado no Proc Natl Acad Sci U S A (2016)

The structure and interactions of periplasmic domains of crucial MmpL membrane proteins from Mycobacterium tuberculosis

Por Chim, Nicholas, Torres, Rodrigo, Liu, Yuqi, Capri, Joe, Batot, Gaëlle, Whitelegge, Julian, Goulding, Celia W.
Publicado no Chem Biol (2015)

Contact-dependent growth inhibition (CDI) and CdiB/CdiA two-partner secretion proteins

Por Willett, Julia L. E., Ruhe, Zachary C., Goulding, Celia W., Low, David A., Hayes, Christopher S.
Publicado no J Mol Biol (2015)

Crystallographic and Spectroscopic Insights into Heme Degradation by Mycobacterium tuberculosis MhuD

Por Graves, Amanda B., Morse, Robert P., Chao, Alex, Iniguez, Angelina, Goulding, Celia W., Liptak, Matthew D.
Publicado em 2014

Fe(2+) Substrate Transport through Ferritin Protein Cage Ion Channels Influences Enzyme Activity and Biomineralization

Por Behera, Rabindra K., Torres, Rodrigo, Tosha, Takehiko, Bradley, Justin M., Goulding, Celia W., Theil, Elizabeth C.
Publicado no J Biol Inorg Chem (2015)

Crystal structure of a major secreted protein of Mycobacterium tuberculosis—MPT63 at 1.5-Å resolution

Por Goulding, Celia W., Parseghian, Angineh, Sawaya, Michael R., Cascio, Duilio, Apostol, Marcin I., Gennaro, Maria Laura, Eisenberg, David
Publicado em 2002