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Fe(2+) Substrate Transport through Ferritin Protein Cage Ion Channels Influences Enzyme Activity and Biomineralization

Ferritins, complex protein nanocages, form internal iron-oxy minerals (Fe(2)O(3).H(2)O), by moving cytoplasmic Fe(2+) through intracage ion channels to cage-embedded enzyme (2Fe(2+)/O(2) oxidoreductase) sites where ferritin biomineralization is initiated. The products of ferritin enzyme activity are...

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Inorg Chem
Hauptverfasser: Behera, Rabindra K., Torres, Rodrigo, Tosha, Takehiko, Bradley, Justin M., Goulding, Celia W., Theil, Elizabeth C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634868/
https://ncbi.nlm.nih.gov/pubmed/26202907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-015-1279-x
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