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Fe(2+) Substrate Transport through Ferritin Protein Cage Ion Channels Influences Enzyme Activity and Biomineralization

Ferritins, complex protein nanocages, form internal iron-oxy minerals (Fe(2)O(3).H(2)O), by moving cytoplasmic Fe(2+) through intracage ion channels to cage-embedded enzyme (2Fe(2+)/O(2) oxidoreductase) sites where ferritin biomineralization is initiated. The products of ferritin enzyme activity are...

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Detalhes bibliográficos
Publicado no:J Biol Inorg Chem
Main Authors: Behera, Rabindra K., Torres, Rodrigo, Tosha, Takehiko, Bradley, Justin M., Goulding, Celia W., Theil, Elizabeth C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4634868/
https://ncbi.nlm.nih.gov/pubmed/26202907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00775-015-1279-x
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