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The Near-iron Transporter (NEAT) Domains of the Anthrax Hemophore IsdX2 Require a Critical Glutamine to Extract Heme from Methemoglobin

Several Gram-positive pathogenic bacteria employ near-iron transporter (NEAT) domains to acquire heme from hemoglobin during infection. However, the structural requirements and mechanism of action for NEAT-mediated heme extraction remains unknown. Bacillus anthracis exhibits a rapid growth rate duri...

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Bibliographische Detailangaben
Hauptverfasser: Honsa, Erin S., Owens, Cedric P., Goulding, Celia W., Maresso, Anthony W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3605663/
https://ncbi.nlm.nih.gov/pubmed/23364793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.430009
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