Differential Function of Lip Residues in the Mechanism and Biology of an Anthrax Hemophore

To replicate in mammalian hosts, bacterial pathogens must acquire iron. The majority of iron is coordinated to the protoporphyrin ring of heme, which is further bound to hemoglobin. Pathogenic bacteria utilize secreted hemophores to acquire heme from heme sources such as hemoglobin. Bacillus anthrac...

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Hlavní autoři: Ekworomadu, MarCia T., Poor, Catherine B., Owens, Cedric P., Balderas, Miriam A., Fabian, Marian, Olson, John S., Murphy, Frank, Balkabasi, Erol, Honsa, Erin S., He, Chuan, Goulding, Celia W., Maresso, Anthony W.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2012
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297588/
https://ncbi.nlm.nih.gov/pubmed/22412371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002559
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