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Heme Transfer to the Bacterial Cell Envelope Occurs via a Secreted Hemophore in the Gram-positive Pathogen Bacillus anthracis

To initiate and sustain an infection in mammals, bacterial pathogens must acquire host iron. However, the host's compartmentalization of large amounts of iron in heme, which is bound primarily by hemoglobin in red blood cells, acts as a barrier to bacterial iron assimilation. Bacillus anthracis...

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Detalhes bibliográficos
Main Authors: Fabian, Marian, Solomaha, Elena, Olson, John S., Maresso, Anthony W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797284/
https://ncbi.nlm.nih.gov/pubmed/19759022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.040915
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