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Unique coupling of mono- and dioxygenase chemistries in a single active site promotes heme degradation
Bacterial pathogens must acquire host iron for survival and colonization. Because free iron is restricted in the host, numerous pathogens have evolved to overcome this limitation by using a family of monooxygenases that mediate the oxidative cleavage of heme into biliverdin, carbon monoxide, and iro...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4833273/ https://ncbi.nlm.nih.gov/pubmed/27006503 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1523333113 |
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