Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis

door Wang, David B., Gitcho, Michael A., Kraemer, Brian C., Klein, Ronald L.
Gepubliceerd in 2011

TDP-43 expression influences amyloid β plaque deposition and tau aggregation

door Davis, Stephani A., Gan, Kok Ann, Dowell, James A., Cairns, Nigel J., Gitcho, Michael A.
Gepubliceerd in Neurobiol Dis (2017)

VCP Mutations Causing Frontotemporal Lobar Degeneration Disrupt Localization of TDP-43 and Induce Cell Death

door Gitcho, Michael A., Strider, Jeffrey, Carter, Deborah, Taylor-Reinwald, Lisa, Forman, Mark S., Goate, Alison M., Cairns, Nigel J.
Gepubliceerd in 2009

POTENTIATION OF INSULIN-STIMULATED GLUCOSE TRANSPORT BY THE AMP-ACTIVATED PROTEIN KINASE

door Ju, Jeong-Sun, Gitcho, Michael A., Casmaer, Carter A., Patil, Pankaj B., Han, Dae-Gyue, Spencer, Susan A., Fisher, Jonathan S.
Gepubliceerd in 2006

Hippocampal neurobiology and function in an aged mouse model of TDP-43 proteinopathy in an APP/PSEN1 background

door Arezoumandan, Sanaz, Cai, Xuezhu, Kalkarni, Praveen, Davis, Stephani A., Wilson, Katherine, Ferris, Craig F., Cairns, Nigel J., Gitcho, Michael A.
Gepubliceerd in Neurosci Lett (2021)

TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics

door Davis, Stephani A., Itaman, Sheed, Khalid-Janney, Christopher M., Sherard, Justin A., Dowell, James A., Cairns, Nigel J., Gitcho, Michael A.
Gepubliceerd in Neurosci Lett (2018)

Pathogenic Cysteine Mutations Affect Progranulin Function and Production of Mature Granulins

door Wang, Jun, Van Damme, Philip, Cruchaga, Carlos, Gitcho, Michael A., Vidal, Jose Manuel, Seijo-Martínez, Manuel, Wang, Lei, Wu, Jane Y., Robberecht, Wim, Goate, Alison
Gepubliceerd in 2009

TARDBP 3′-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy

door Gitcho, Michael A., Bigio, Eileen H., Mishra, Manjari, Johnson, Nancy, Weintraub, Sandra, Mesulam, Marsel, Rademakers, Rosa, Chakraverty, Sumi, Cruchaga, Carlos, Morris, John C., Goate, Alison M., Cairns, Nigel J.
Gepubliceerd in 2009

FUS immunogold labelling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS prote...

door Page, Tristan, Gitcho, Michael A., Mosaheb, Sabrina, Carter, Deborah, Chakraverty, Sumi, Perry, Robert H., Bigio, Eileen H., Gearing, Marla, Ferrer, Isidre, Goate, Alison M., Cairns, Nigel J., Thorpe, Julian R.
Gepubliceerd in 2011

Selective Forelimb Impairment in Rats Expressing a Pathological TDP-43 25 kDa C-terminal Fragment to Mimic Amyotrophic Lateral Sclerosis

door Dayton, Robert D, Gitcho, Michael A, Orchard, Elysse A, Wilson, Jon D, Wang, David B, Cain, Cooper D, Johnson, Jeffrey A, Zhang, Yong-Jie, Petrucelli, Leonard, Mathis, J Michael, Klein, Ronald L
Gepubliceerd in 2013

Initial gene vector dosing for studying symptomatology of amyotrophic lateral sclerosis in non-human primates

door Jackson, Kasey L., Dayton, Robert D., Fisher-Perkins, Jeanne M., Didier, Peter J., Baker, Kate C., Weimer, Maria, Gutierrez, Amparo, Cain, Cooper D., Mathis, J. Michael, Gitcho, Michael A., Bunnell, Bruce A., Klein, Ronald L.
Gepubliceerd in J Med Primatol (2015)

Molecular Characterization of Novel Progranulin (GRN) Mutations in Frontotemporal Dementia

door Mukherjee, Odity, Wang, Jun, Gitcho, Michael, Chakraverty, Sumi, Taylor-Reinwald, Lisa, Shears, Shantia, Kauwe, John S.K., Norton, Joanne, Levitch, Denise, Bigio, Eileen H., Hatanpaa, Kimmo J., White, Charles L., Morris, John C., Cairns, Nigel J., Goate, Alison
Gepubliceerd in 2008

TDP-43 A315T Mutation in Familial Motor Neuron Disease

door Gitcho, Michael A., Baloh, Robert H., Chakraverty, Sumi, Mayo, Kevin, Norton, Joanne B., Levitch, Denise, Hatanpaa, Kimmo J., White, Charles L., Bigio, Eileen H., Caselli, Richard, Baker, Matt, Al-Lozi, Muhammad T., Morris, John C., Pestronk, Alan, Rademakers, Rosa, Goate, Alison M., Cairns, Nigel J.
Gepubliceerd in 2008

HDDD2 Is a Familial Frontotemporal Lobar Degeneration with Ubiquitin-Positive, Tau-Negative Inclusions Caused by a Missense Mutation in the Signal Peptide of Progranulin

door Mukherjee, Odity, Pastor, Pau, Cairns, Nigel J., Chakraverty, Sumi, Kauwe, John S. K., Shears, Shantia, Behrens, Maria I., Budde, John, Hinrichs, Anthony L., Norton, Joanne, Levitch, Denise, Taylor-Reinwald, Lisa, Gitcho, Michael, Tu, P.-H., Grinberg, Lea Tenenholz, Liscic, Rajka M., Armendariz, Javier, Morris, John C., Goate, Alison M.
Gepubliceerd in 2006

TDP-43 in Familial and Sporadic Frontotemporal Lobar Degeneration with Ubiquitin Inclusions

door Cairns, Nigel J., Neumann, Manuela, Bigio, Eileen H., Holm, Ida E., Troost, Dirk, Hatanpaa, Kimmo J., Foong, Chan, White, Charles L., Schneider, Julie A., Kretzschmar, Hans A., Carter, Deborah, Taylor-Reinwald, Lisa, Paulsmeyer, Katherine, Strider, Jeffrey, Gitcho, Michael, Goate, Alison M., Morris, John C., Mishra, Manjari, Kwong, Linda K., Stieber, Anna, Xu, Yan, Forman, Mark S., Trojanowski, John Q., Lee, Virginia M.-Y., Mackenzie, Ian R.A.
Gepubliceerd in 2007