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TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics

Transactive response DNA-binding protein of 43kDa (TDP-43) functions as a heterogeneous nuclear ribonucleoprotein and is the major pathological protein in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis/motor neuron disease (ALS/MND). TDP-43 pathology may also be present a...

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Detalhes bibliográficos
Publicado no:Neurosci Lett
Main Authors: Davis, Stephani A., Itaman, Sheed, Khalid-Janney, Christopher M., Sherard, Justin A., Dowell, James A., Cairns, Nigel J., Gitcho, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5975202/
https://ncbi.nlm.nih.gov/pubmed/29715546
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2018.04.053
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