Genetic strategies to study TDP-43 in rodents and to develop preclinical therapeutics for amyotrophic lateral sclerosis

von Wang, David B., Gitcho, Michael A., Kraemer, Brian C., Klein, Ronald L.
Veröffentlicht 2011

TDP-43 expression influences amyloid β plaque deposition and tau aggregation

von Davis, Stephani A., Gan, Kok Ann, Dowell, James A., Cairns, Nigel J., Gitcho, Michael A.
Veröffentlicht in Neurobiol Dis (2017)

VCP Mutations Causing Frontotemporal Lobar Degeneration Disrupt Localization of TDP-43 and Induce Cell Death

von Gitcho, Michael A., Strider, Jeffrey, Carter, Deborah, Taylor-Reinwald, Lisa, Forman, Mark S., Goate, Alison M., Cairns, Nigel J.
Veröffentlicht 2009

POTENTIATION OF INSULIN-STIMULATED GLUCOSE TRANSPORT BY THE AMP-ACTIVATED PROTEIN KINASE

von Ju, Jeong-Sun, Gitcho, Michael A., Casmaer, Carter A., Patil, Pankaj B., Han, Dae-Gyue, Spencer, Susan A., Fisher, Jonathan S.
Veröffentlicht 2006

Hippocampal neurobiology and function in an aged mouse model of TDP-43 proteinopathy in an APP/PSEN1 background

von Arezoumandan, Sanaz, Cai, Xuezhu, Kalkarni, Praveen, Davis, Stephani A., Wilson, Katherine, Ferris, Craig F., Cairns, Nigel J., Gitcho, Michael A.
Veröffentlicht in Neurosci Lett (2021)

TDP-43 interacts with mitochondrial proteins critical for mitophagy and mitochondrial dynamics

von Davis, Stephani A., Itaman, Sheed, Khalid-Janney, Christopher M., Sherard, Justin A., Dowell, James A., Cairns, Nigel J., Gitcho, Michael A.
Veröffentlicht in Neurosci Lett (2018)

Pathogenic Cysteine Mutations Affect Progranulin Function and Production of Mature Granulins

von Wang, Jun, Van Damme, Philip, Cruchaga, Carlos, Gitcho, Michael A., Vidal, Jose Manuel, Seijo-Martínez, Manuel, Wang, Lei, Wu, Jane Y., Robberecht, Wim, Goate, Alison
Veröffentlicht 2009

TARDBP 3′-UTR variant in autopsy-confirmed frontotemporal lobar degeneration with TDP-43 proteinopathy

von Gitcho, Michael A., Bigio, Eileen H., Mishra, Manjari, Johnson, Nancy, Weintraub, Sandra, Mesulam, Marsel, Rademakers, Rosa, Chakraverty, Sumi, Cruchaga, Carlos, Morris, John C., Goate, Alison M., Cairns, Nigel J.
Veröffentlicht 2009

FUS immunogold labelling TEM analysis of the neuronal cytoplasmic inclusions of neuronal intermediate filament inclusion disease: a frontotemporal lobar degeneration with FUS prote...

von Page, Tristan, Gitcho, Michael A., Mosaheb, Sabrina, Carter, Deborah, Chakraverty, Sumi, Perry, Robert H., Bigio, Eileen H., Gearing, Marla, Ferrer, Isidre, Goate, Alison M., Cairns, Nigel J., Thorpe, Julian R.
Veröffentlicht 2011

Selective Forelimb Impairment in Rats Expressing a Pathological TDP-43 25 kDa C-terminal Fragment to Mimic Amyotrophic Lateral Sclerosis

von Dayton, Robert D, Gitcho, Michael A, Orchard, Elysse A, Wilson, Jon D, Wang, David B, Cain, Cooper D, Johnson, Jeffrey A, Zhang, Yong-Jie, Petrucelli, Leonard, Mathis, J Michael, Klein, Ronald L
Veröffentlicht 2013

Initial gene vector dosing for studying symptomatology of amyotrophic lateral sclerosis in non-human primates

von Jackson, Kasey L., Dayton, Robert D., Fisher-Perkins, Jeanne M., Didier, Peter J., Baker, Kate C., Weimer, Maria, Gutierrez, Amparo, Cain, Cooper D., Mathis, J. Michael, Gitcho, Michael A., Bunnell, Bruce A., Klein, Ronald L.
Veröffentlicht in J Med Primatol (2015)

Molecular Characterization of Novel Progranulin (GRN) Mutations in Frontotemporal Dementia

von Mukherjee, Odity, Wang, Jun, Gitcho, Michael, Chakraverty, Sumi, Taylor-Reinwald, Lisa, Shears, Shantia, Kauwe, John S.K., Norton, Joanne, Levitch, Denise, Bigio, Eileen H., Hatanpaa, Kimmo J., White, Charles L., Morris, John C., Cairns, Nigel J., Goate, Alison
Veröffentlicht 2008

TDP-43 A315T Mutation in Familial Motor Neuron Disease

von Gitcho, Michael A., Baloh, Robert H., Chakraverty, Sumi, Mayo, Kevin, Norton, Joanne B., Levitch, Denise, Hatanpaa, Kimmo J., White, Charles L., Bigio, Eileen H., Caselli, Richard, Baker, Matt, Al-Lozi, Muhammad T., Morris, John C., Pestronk, Alan, Rademakers, Rosa, Goate, Alison M., Cairns, Nigel J.
Veröffentlicht 2008

HDDD2 Is a Familial Frontotemporal Lobar Degeneration with Ubiquitin-Positive, Tau-Negative Inclusions Caused by a Missense Mutation in the Signal Peptide of Progranulin

von Mukherjee, Odity, Pastor, Pau, Cairns, Nigel J., Chakraverty, Sumi, Kauwe, John S. K., Shears, Shantia, Behrens, Maria I., Budde, John, Hinrichs, Anthony L., Norton, Joanne, Levitch, Denise, Taylor-Reinwald, Lisa, Gitcho, Michael, Tu, P.-H., Grinberg, Lea Tenenholz, Liscic, Rajka M., Armendariz, Javier, Morris, John C., Goate, Alison M.
Veröffentlicht 2006

TDP-43 in Familial and Sporadic Frontotemporal Lobar Degeneration with Ubiquitin Inclusions

von Cairns, Nigel J., Neumann, Manuela, Bigio, Eileen H., Holm, Ida E., Troost, Dirk, Hatanpaa, Kimmo J., Foong, Chan, White, Charles L., Schneider, Julie A., Kretzschmar, Hans A., Carter, Deborah, Taylor-Reinwald, Lisa, Paulsmeyer, Katherine, Strider, Jeffrey, Gitcho, Michael, Goate, Alison M., Morris, John C., Mishra, Manjari, Kwong, Linda K., Stieber, Anna, Xu, Yan, Forman, Mark S., Trojanowski, John Q., Lee, Virginia M.-Y., Mackenzie, Ian R.A.
Veröffentlicht 2007