Protein Kinase C

Por Gescher, A.
Publicado em 1993

Towards selective pharmacological modulation of protein kinase C--opportunities for the development of novel antineoplastic agents.

Por Gescher, A.
Publicado em 1992

Drug metabolism interactions with cytotoxic agents in mice [proceedings]

Por Gescher, A., Green, A. E.
Publicado em 1979

Comparison of ability of protein kinase C inhibitors to arrest cell growth and to alter cellular protein kinase C localisation.

Por Courage, C., Budworth, J., Gescher, A.
Publicado em 1995

Differential effects of staurosporine analogues on cell cycle, growth and viability in A549 cells.

Por Courage, C., Snowden, R., Gescher, A.
Publicado em 1996

Co-ordinate loss of protein kinase C and multidrug resistance gene expression in revertant MCF-7/Adr breast carcinoma cells.

Por Budworth, J., Gant, T. W., Gescher, A.
Publicado em 1997

Cancer chemoprevention: lessons learned and future directions

Por Brenner, D E, Gescher, A J
Publicado em 2005

In vitro biotransformation of carbinolamine metabolites of cytotoxic dimethyltriazenes [proceedings]

Por Gescher, A., Hickman, J. A., Stevens, M. F.
Publicado em 1979

Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin

Por Perkins, S, Clarke, A R, Steward, W, Gescher, A
Publicado em 2003

Familiar drugs may prevent cancer

Por Sharma, R, Gescher, A, O'Byrne, K, Steward, W
Publicado em 2001

Regulation of P-glycoprotein 1 and 2 gene expression and protein activity in two MCF-7/Dox cell line subclones.

Por Davies, R., Budworth, J., Riley, J., Snowden, R., Gescher, A., Gant, T. W.
Publicado em 1996

Comparison of staurosporine and four analogues: their effects on growth, rhodamine 123 retention and binding to P-glycoprotein in multidrug-resistant MCF-7/Adr cells.

Por Budworth, J., Davies, R., Malkhandi, J., Gant, T. W., Ferry, D. R., Gescher, A.
Publicado em 1996

N-methylformamide: antitumour activity and metabolism in mice.

Por Gescher, A., Gibson, N. W., Hickman, J. A., Langdon, S. P., Ross, D., Atassi, G.
Publicado em 1982

Evaluation of the cancer chemopreventive efficacy of rice bran in genetic mouse models of breast, prostate and intestinal carcinogenesis

Por Verschoyle, R D, Greaves, P, Cai, H, Edwards, R E, Steward, W P, Gescher, A J
Publicado em 2007

Differences between human breast cell lines in susceptibility towards growth inhibition by genistein

Por Dampier, K, Hudson, E A, Howells, L M, Manson, M M, Walker, R A, Gescher, A
Publicado em 2001

Induction of cell death by stimulation of protein kinase C in human epithelial cells expressing a mutant ras oncogene: a potential therapeutic target.

Por Hall-Jackson, C. A., Jones, T., Eccles, N. G., Dawson, T. P., Bond, J. A., Gescher, A., Wynford-Thomas, D.
Publicado em 1998

Establishment of a murine leukaemia cell line resistant to the growth-inhibitory effect of bryostatin 1.

Por Prendiville, J., McGown, A. T., Gescher, A., Dickson, A. J., Courage, C., Pettit, G. R., Crowther, D., Fox, B. W.
Publicado em 1994

Growth-inhibitory and cell cycle-arresting properties of the rice bran constituent tricin in human-derived breast cancer cells in vitro and in nude mice in vivo

Por Cai, H, Hudson, E A, Mann, P, Verschoyle, R D, Greaves, P, Manson, M M, Steward, W P, Gescher, A J
Publicado em 2004

Phase I randomised double-blind pilot study of micronized resveratrol (SRT501) in patients with hepatic metastases - safety, pharmacokinetics and pharmacodynamics

Por Howells, L. M., Berry, D. P., Elliott, P.J., Jacobson, E. W., Hoffmann, E., Hegarty, B., Brown, K., Steward, W. P., Gescher, A. J.
Publicado em 2011

Pulmonary availability of isotretinoin in rats after inhalation of a powder aerosol

Por Raleigh, S M, Verschoyle, R D, Bowskill, C, Pastorino, U, Staniforth, J N, Steele, F, Dinsdale, D, Carthew, P, Lim, C K, Silvester, J, Gescher, A
Publicado em 2000