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Establishment of a murine leukaemia cell line resistant to the growth-inhibitory effect of bryostatin 1.

Bryostatin 1 is a novel macrocyclic lactone activator of protein kinase C (PKC) which has clinical potential as an anti-cancer agent. The mechanism of action of this agent is unknown, but protein kinase C has been implicated. In order to investigate this possibility, we have developed P388 sublines...

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Detalhes bibliográficos
Main Authors: Prendiville, J., McGown, A. T., Gescher, A., Dickson, A. J., Courage, C., Pettit, G. R., Crowther, D., Fox, B. W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2033429/
https://ncbi.nlm.nih.gov/pubmed/7917900
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