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Regulation of P-glycoprotein 1 and 2 gene expression and protein activity in two MCF-7/Dox cell line subclones.

The MCF-7 doxorubicin-resistant cell line MCF-7/Dox has been used extensively for studies of the multidrug resistance phenomenon. Using fluorescence-activated cell sorting (FACS), these cells were separated into two populations on the basis of rhodamine 123 (R123) accumulation. We designated these a...

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Main Authors: Davies, R., Budworth, J., Riley, J., Snowden, R., Gescher, A., Gant, T. W.
格式: Artigo
語言:Inglês
出版: Nature Publishing Group 1996
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2074442/
https://ncbi.nlm.nih.gov/pubmed/8562335
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