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Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin

The nonsteroidal anti-inflammatory drug aspirin and the spice curcumin retard adenoma formation when administered long-term to Apc(Min/+) mice, a model of human familial adenomatous polyposis coli. Both agents interfere with cyclooxygenase activity. When aspirin is administered to Apc(Min/+) mice on...

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Hlavní autoři: Perkins, S, Clarke, A R, Steward, W, Gescher, A
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2003
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2741037/
https://ncbi.nlm.nih.gov/pubmed/12778080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6600900
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