Early afterdepolarisation tendency as a simulated pro-arrhythmic risk indicator

Por McMillan, Beth, Gavaghan, David J., Mirams, Gary R.
Publicado no Toxicol Res (Camb) (2017)

Inference of Intramural Wavefront Orientation from Optical Recordings in Realistic Whole-Heart Models

Por Bishop, Martin J., Rodriguez, Blanca, Trayanova, Natalia, Gavaghan, David J.
Publicado em 2006

Hodgkin–Huxley revisited: reparametrization and identifiability analysis of the classic action potential model with approximate Bayesian methods

Por Daly, Aidan C., Gavaghan, David J., Holmes, Chris, Cooper, Jonathan
Publicado no R Soc Open Sci (2015)

Comparing two sequential Monte Carlo samplers for exact and approximate Bayesian inference on biological models

Por Daly, Aidan C., Cooper, Jonathan, Gavaghan, David J., Holmes, Chris
Publicado no J R Soc Interface (2017)

Photon Scattering Effects in Optical Mapping of Propagation and Arrhythmogenesis in the Heart

Por Bishop, Martin J., Gavaghan, David J., Trayanova, Natalia A., Rodriguez, Blanca
Publicado em 2007

Hierarchical Bayesian inference for ion channel screening dose-response data

Por Johnstone, Ross H, Bardenet, Rémi, Gavaghan, David J, Mirams, Gary R
Publicado no Wellcome Open Res (2017)

Uncertainty quantification of fast sodium current steady-state inactivation for multi-scale models of cardiac electrophysiology

Por Pathmanathan, Pras, Shotwell, Matthew S., Gavaghan, David J., Cordeiro, Jonathan M., Gray, Richard A.
Publicado no Prog Biophys Mol Biol (2015)

The Role of Photon Scattering in Voltage-Calcium Fluorescent Recordings of Ventricular Fibrillation

Por Bishop, Martin J., Rowley, Alexander, Rodriguez, Blanca, Plank, Gernot, Gavaghan, David J., Bub, Gil
Publicado em 2011

Pooling data for Number Needed to Treat: no problems for apples

Por Wiffen Phillip, Edwards Jayne E, Gavaghan David J, Moore R Andrew, McQuay Henry J
Publicado em 2002-01-01

Pooling data for Number Needed to Treat: no problems for apples

Por Moore, R Andrew, Gavaghan, David J, Edwards, Jayne E, Wiffen, Phillip, McQuay, Henry J
Publicado em 2002

Synthesis of Voltage-Sensitive Optical Signals: Application to Panoramic Optical Mapping

Por Bishop, Martin J., Rodriguez, Blanca, Eason, James, Whiteley, Jonathan P., Trayanova, Natalia, Gavaghan, David J.
Publicado em 2006

The Free Energy Landscape of Dimerization of a Membrane Protein, NanC

Por Dunton, Thomas A., Goose, Joseph E., Gavaghan, David J., Sansom, Mark S. P., Osborne, James M.
Publicado em 2014

The Role of Photon Scattering in Optical Signal Distortion during Arrhythmia and Defibrillation

Por Bishop, Martin J., Rodriguez, Blanca, Qu, Fujian, Efimov, Igor R., Gavaghan, David J., Trayanova, Natalia A.
Publicado em 2007

Comparing individual-based approaches to modelling the self-organization of multicellular tissues

Por Osborne, James M., Fletcher, Alexander G., Pitt-Francis, Joe M., Maini, Philip K., Gavaghan, David J.
Publicado no PLoS Comput Biol (2017)

A Two-Dimensional Model of the Colonic Crypt Accounting for the Role of the Basement Membrane and Pericryptal Fibroblast Sheath

Por Dunn, Sara-Jane, Appleton, Paul L., Nelson, Scott A., Näthke, Inke S., Gavaghan, David J., Osborne, James M.
Publicado em 2012

Evaluation of an in silico cardiac safety assay: Using ion channel screening data to predict QT interval changes in the rabbit ventricular wedge

Por Beattie, Kylie A., Luscombe, Chris, Williams, Geoff, Munoz-Muriedas, Jordi, Gavaghan, David J., Cui, Yi, Mirams, Gary R.
Publicado em 2013

Development of an anatomically detailed MRI-derived rabbit ventricular model and assessment of its impact on simulations of electrophysiological function

Por Bishop, Martin J., Plank, Gernot, Burton, Rebecca A. B., Schneider, Jürgen E., Gavaghan, David J., Grau, Vicente, Kohl, Peter
Publicado em 2010

Cardiac tissue slices: preparation, handling, and successful optical mapping

Por Wang, Ken, Lee, Peter, Mirams, Gary R., Sarathchandra, Padmini, Borg, Thomas K., Gavaghan, David J., Kohl, Peter, Bollensdorff, Christian
Publicado no Am J Physiol Heart Circ Physiol (2015)

Variability in high-throughput ion-channel screening data and consequences for cardiac safety assessment

Por Elkins, Ryan C., Davies, Mark R., Brough, Stephen J., Gavaghan, David J., Cui, Yi, Abi-Gerges, Najah, Mirams, Gary R.
Publicado em 2013

Prediction of Thorough QT study results using action potential simulations based on ion channel screens

Por Mirams, Gary R., Davies, Mark R., Brough, Stephen J., Bridgland-Taylor, Matthew H., Cui, Yi, Gavaghan, David J., Abi-Gerges, Najah
Publicado no J Pharmacol Toxicol Methods (2014)