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Hierarchical Bayesian inference for ion channel screening dose-response data

Dose-response (or ‘concentration-effect’) relationships commonly occur in biological and pharmacological systems and are well characterised by Hill curves. These curves are described by an equation with two parameters: the inhibitory concentration 50% (IC50); and the Hill coefficient. Typically just...

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Detalhes bibliográficos
Publicado no:Wellcome Open Res
Main Authors: Johnstone, Ross H, Bardenet, Rémi, Gavaghan, David J, Mirams, Gary R
Formato: Artigo
Idioma:Inglês
Publicado em: F1000Research 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5134333/
https://ncbi.nlm.nih.gov/pubmed/27918599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/wellcomeopenres.9945.2
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