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Hodgkin–Huxley revisited: reparametrization and identifiability analysis of the classic action potential model with approximate Bayesian methods

As cardiac cell models become increasingly complex, a correspondingly complex ‘genealogy’ of inherited parameter values has also emerged. The result has been the loss of a direct link between model parameters and experimental data, limiting both reproducibility and the ability to re-fit to new data....

詳細記述

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書誌詳細
出版年:R Soc Open Sci
主要な著者: Daly, Aidan C., Gavaghan, David J., Holmes, Chris, Cooper, Jonathan
フォーマット: Artigo
言語:Inglês
出版事項: The Royal Society Publishing 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4807457/
https://ncbi.nlm.nih.gov/pubmed/27019736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsos.150499
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