Recent Advances in the Discovery of Norovirus Therapeutics: Miniperspective

Por Kim, Yunjeong, Galasiti Kankanamalage, Anushka C., Chang, Kyeong-Ok, Groutas, William C.
Publicado no J Med Chem (2015)

Anti-Norovirus Therapeutics: A Patent Review (2010–2015)

Por Galasiti Kankanamalage, Anushka C., Weerawarna, Pathum M., Kim, Yunjeong, Chang, Kyeong-Ok, Groutas, William C.
Publicado no Expert Opin Ther Pat (2016)

Protease inhibitors broadly effective against feline, ferret and mink coronaviruses

Por Perera, Krishani Dinali, Galasiti Kankanamalage, Anushka C., Rathnayake, Athri D., Honeyfield, Amanda, Groutas, William, Chang, Kyeong-Ok, Kim, Yunjeong
Publicado no Antiviral Res (2018)

Reversal of the Progression of Fatal Coronavirus Infection in Cats by a Broad-Spectrum Coronavirus Protease Inhibitor

Por Kim, Yunjeong, Liu, Hongwei, Galasiti Kankanamalage, Anushka C., Weerasekara, Sahani, Hua, Duy H., Groutas, William C., Chang, Kyeong-Ok, Pedersen, Niels C.
Publicado no PLoS Pathog (2016)

Efficacy of a 3C-like protease inhibitor in treating various forms of acquired feline infectious peritonitis

Por Pedersen, Niels C, Kim, Yunjeong, Liu, Hongwei, Galasiti Kankanamalage, Anushka C, Eckstrand, Chrissy, Groutas, William C, Bannasch, Michael, Meadows, Juliana M, Chang, Kyeong-Ok
Publicado no J Feline Med Surg (2017)

Design, Synthesis, and Evaluation of a Novel Series of Macrocyclic Inhibitors of Norovirus 3CL Protease

Por Damalanka, Vishnu C., Kim, Yunjeong, Galasiti Kankanamalage, Anushka C., Lushington, Gerald H., Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Publicado no Eur J Med Chem (2016)

Putative Structural Rearrangements Associated with the Interaction of Macrocyclic Inhibitors with Norovirus 3CL Protease

Por Galasiti Kankanamalage, Anushka C., Weerawarna, Pathum M., Rathnayake, Athri D., Kim, Yunjeong, Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Publicado no Proteins (2019)

Structure-based design and synthesis of triazole-based macrocyclic inhibitors of norovirus protease: Structural, biochemical, spectroscopic, and antiviral studies

Por Weerawarna, Pathum M., Kim, Yunjeong, Galasiti Kankanamalage, Anushka C., Damalanka, Vishnu C., Lushington, Gerald H., Alliston, Kevin R., Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Publicado no Eur J Med Chem (2016)

Oxadiazole-Based Cell Permeable Macrocyclic Transition State Inhibitors of Norovirus 3CL Protease

Por Damalanka, Vishnu C., Kim, Yunjeong, Alliston, Kevin R., Weerawarna, Pathum M., Galasiti Kankanamalage, Anushka C., Lushington, Gerald H., Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Publicado no J Med Chem (2016)

Structure-guided Design, Synthesis and Evaluation of Oxazolidinone-based Inhibitors of Norovirus 3CL Protease

Por Damalanka, Vishnu C., Kim, Yunjeong, Galasiti Kankanamalage, Anushka C., Rathnayake, Athri D., Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Nguyen, Harry Nhat, Lushington, Gerald H., Chang, Kyeong-Ok, Groutas, William C.
Publicado no Eur J Med Chem (2017)

Structure-guided design of potent and permeable inhibitors of MERS coronavirus 3CL protease that utilize a piperidine moiety as a novel design element

Por Galasiti Kankanamalage, Anushka C., Kim, Yunjeong, Damalanka, Vishnu C., Rathnayake, Athri D., Fehr, Anthony R., Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Lushington, Gerald H., Perlman, Stanley, Chang, Kyeong-Ok, Groutas, William C.
Publicado no Eur J Med Chem (2018)

Structure-Based Exploration and Exploitation of the S(4) Subsite of Norovirus 3CL Protease in the Design of Potent and Permeable Inhibitors

Por Galasiti Kankanamalage, Anushka C., Kim, Yunjeong, Rathnayake, Athri D., Damalanka, Vishnu C., Weerawarna, Pathum M., Doyle, Sean T., Alsoudi, Amer F., Padmasankha Dissanayake, D. M., Lushington, Gerald H., Mehzabeen, Nurjahan, Battaile, Kevin P., Lovell, Scott, Chang, Kyeong-Ok, Groutas, William C.
Publicado no Eur J Med Chem (2016)