Molecular basis for substrate recognition and drug resistance from 1.1 to 1.6 Å resolution crystal structures of HIV-1 protease mutants with substrate analogs

Por Tie, Yunfeng, Boross, Peter I., Wang, Yuan-Fang, Gaddis, Laquasha, Liu, Fengling, Chen, Xianfeng, Tozser, Jozsef, Harrison, Robert W., Weber, Irene T.
Publicado em 2005

Novel bis-Tetrahydrofuranylurethane-Containing Nonpeptidic Protease Inhibitor (PI) UIC-94017 (TMC114) with Potent Activity against Multi-PI-Resistant Human Immunodeficiency Virus I...

Por Koh, Yasuhiro, Nakata, Hirotomo, Maeda, Kenji, Ogata, Hiromi, Bilcer, Geoffrey, Devasamudram, Thippeswamy, Kincaid, John F., Boross, Peter, Wang, Yuan-Fang, Tie, Yunfeng, Volarath, Patra, Gaddis, Laquasha, Harrison, Robert W., Weber, Irene T., Ghosh, Arun K., Mitsuya, Hiroaki
Publicado em 2003