HIV-1 transcriptional regulation in the central nervous system and implications for HIV cure research

Por Churchill, Melissa J., Cowley, Daniel J., Wesselingh, Steve L., Gorry, Paul R., Gray, Lachlan R.
Publicado no J Neurovirol (2014)

CoRSeq(V3-C): a novel HIV-1 subtype C specific V3 sequence based coreceptor usage prediction algorithm

Por Cashin, Kieran, Gray, Lachlan R, Jakobsen, Martin R, Sterjovski, Jasminka, Churchill, Melissa J, Gorry, Paul R
Publicado em 2013

Is the central nervous system a reservoir of HIV-1?

Por Gray, Lachlan R., Roche, Michael, Flynn, Jacqueline K., Wesselingh, Steve L., Gorry, Paul R., Churchill, Melissa J.
Publicado em 2014

Reduced Basal Transcriptional Activity of Central Nervous System-Derived HIV Type 1 Long Terminal Repeats

Por Gray, Lachlan R., Cowley, Daniel, Crespan, Emma, Welsh, Casey, Mackenzie, Charlene, Wesselingh, Steve L., Gorry, Paul R., Churchill, Melissa J.
Publicado em 2013

CD4 and MHC class I down-modulation activities of nef alleles from brain- and lymphoid tissue-derived primary HIV-1 isolates

Por Gray, Lachlan R., Gabuzda, Dana, Cowley, Daniel, Ellett, Anne, Chiavaroli, Lisa, Wesselingh, Steven L., Churchill, Melissa J., Gorry, Paul R.
Publicado no J Neurovirol (2010)

Inhibition of Catechol-O-methyl Transferase (COMT) by Tolcapone Restores Reductions in Microtubule-associated Protein 2 (MAP2) and Synaptophysin (SYP) Following Exposure of Neurona...

Por Lee, Ting Ting, Chana, Gursharan, Gorry, Paul R., Ellett, Anne, Bousman, Chad A., Churchill, Melissa J., Gray, Lachlan R., Everall, Ian P.
Publicado no J Neurovirol (2015)

Alternative Coreceptor Requirements for Efficient CCR5- and CXCR4-Mediated HIV-1 Entry into Macrophages

Por Cashin, Kieran, Roche, Michael, Sterjovski, Jasminka, Ellett, Anne, Gray, Lachlan R., Cunningham, Anthony L., Ramsland, Paul A., Churchill, Melissa J., Gorry, Paul R.
Publicado em 2011

A new way of measuring apoptosis by absolute quantitation of inter-nucleosomally fragmented genomic DNA

Por Hooker, David J., Mobarok, Masqura, Anderson, Jenny L., Rajasuriar, Reena, Gray, Lachlan R., Ellett, Anne M., Lewin, Sharon R., Gorry, Paul R., Cherry, Catherine L.
Publicado em 2012

Macrophage-tropic HIV-1 variants from brain demonstrate alterations in the way gp120 engages both CD4 and CCR5

Por Salimi, Hamid, Roche, Michael, Webb, Nicholas, Gray, Lachlan R., Chikere, Kelechi, Sterjovski, Jasminka, Ellett, Anne, Wesselingh, Steve L., Ramsland, Paul A., Lee, Benhur, Churchill, Melissa J., Gorry, Paul R.
Publicado em 2013

HIV-1 Entry and Trans-Infection of Astrocytes Involves CD81 Vesicles

Por Gray, Lachlan R., Turville, Stuart G., HItchen, Tina L., Cheng, Wan-Jung, Ellett, Anne M., Salimi, Hamid, Roche, Michael J., Wesselingh, Steve L., Gorry, Paul R., Churchill, Melissa J.
Publicado em 2014

An altered and more efficient mechanism of CCR5 engagement contributes to macrophage tropism of CCR5-using HIV-1 Envelopes

Por Sterjovski, Jasminka, Roche, Michael, Churchill, Melissa J., Ellett, Anne, Farrugia, William, Gray, Lachlan R., Cowley, Daniel, Poumbourios, Pantelis, Lee, Benhur, Wesselingh, Steven L., Cunningham, Anthony L., Ramsland, Paul A., Gorry, Paul R.
Publicado em 2010

The NRTIs Lamivudine, Stavudine and Zidovudine Have Reduced HIV-1 Inhibitory Activity in Astrocytes

Por Gray, Lachlan R., Tachedjian, Gilda, Ellett, Anne M., Roche, Michael J., Cheng, Wan-Jung, Guillemin, Gilles J., Brew, Bruce J., Turville, Stuart G., Wesselingh, Steve L., Gorry, Paul R., Churchill, Melissa J.
Publicado em 2013

Ex Vivo Response to Histone Deacetylase (HDAC) Inhibitors of the HIV Long Terminal Repeat (LTR) Derived from HIV-Infected Patients on Antiretroviral Therapy

Por Lu, Hao K., Gray, Lachlan R., Wightman, Fiona, Ellenberg, Paula, Khoury, Gabriela, Cheng, Wan-Jung, Mota, Talia M., Wesselingh, Steve, Gorry, Paul R., Cameron, Paul U., Churchill, Melissa J., Lewin, Sharon R.
Publicado no PLoS One (2014)

Reliable Genotypic Tropism Tests for the Major HIV-1 Subtypes

Por Cashin, Kieran, Gray, Lachlan R., Harvey, Katherine L., Perez-Bercoff, Danielle, Lee, Guinevere Q., Sterjovski, Jasminka, Roche, Michael, Demarest, James F., Drummond, Fraser, Harrigan, P. Richard, Churchill, Melissa J., Gorry, Paul R.
Publicado no Sci Rep (2015)

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

Por Wang Bin, Saksena Nitin, Purcell Damian FJ, Dunfee Rebecca L, Roche Michael J, Gray Lachlan R, Ellett Anne, Churchill Melissa J, Sterjovski Jasminka, Sonza Secondo, Wesselingh Steven L, Karlsson Ingrid, Fenyo Eva-Maria, Gabuzda Dana, Cunningham Anthony L, Gorry Paul R
Publicado em 2007-12-01

Asn 362 in gp120 contributes to enhanced fusogenicity by CCR5-restricted HIV-1 envelope glycoprotein variants from patients with AIDS

Por Sterjovski, Jasminka, Churchill, Melissa J, Ellett, Anne, Gray, Lachlan R, Roche, Michael J, Dunfee, Rebecca L, Purcell, Damian FJ, Saksena, Nitin, Wang, Bin, Sonza, Secondo, Wesselingh, Steven L, Karlsson, Ingrid, Fenyo, Eva-Maria, Gabuzda, Dana, Cunningham, Anthony L, Gorry, Paul R
Publicado em 2007

HIV latency can be established in proliferating and non-proliferating resting CD4(+) T cells in vitro: implications for latency reversal

Por MOSO, Michael A., ANDERSON, Jenny L., ADIKARI, Samantha, GRAY, Lachlan R., KHOURY, Georges, CHANG, J. Judy, JACOBSON, Jonathan C., ELLETT, Anne M., CHENG, Wan-Jung, SALEH, Suha, ZAUNDERS, John J., PURCELL, Damian F.J., CAMERON, Paul U., CHURCHILL, Melissa J., LEWIN, Sharon R., LU, Hao K.
Publicado no AIDS (2019)

A common mechanism of clinical HIV-1 resistance to the CCR5 antagonist maraviroc despite divergent resistance levels and lack of common gp120 resistance mutations

Por Roche, Michael, Salimi, Hamid, Duncan, Renee, Wilkinson, Brendan L, Chikere, Kelechi, Moore, Miranda S, Webb, Nicholas E, Zappi, Helena, Sterjovski, Jasminka, Flynn, Jacqueline K, Ellett, Anne, Gray, Lachlan R, Lee, Benhur, Jubb, Becky, Westby, Mike, Ramsland, Paul A, Lewin, Sharon R, Payne, Richard J, Churchill, Melissa J, Gorry, Paul R
Publicado em 2013

Longitudinal Analysis of CCR5 and CXCR4 Usage in a Cohort of Antiretroviral Therapy-Naïve Subjects with Progressive HIV-1 Subtype C Infection

Por Jakobsen, Martin R., Cashin, Kieran, Roche, Michael, Sterjovski, Jasminka, Ellett, Anne, Borm, Katharina, Flynn, Jacqueline, Erikstrup, Christian, Gouillou, Maelenn, Gray, Lachlan R., Saksena, Nitin K., Wang, Bin, Purcell, Damian F. J., Kallestrup, Per, Zinyama-Gutsire, Rutendo, Gomo, Exnevia, Ullum, Henrik, Østergaard, Lars, Lee, Benhur, Ramsland, Paul A., Churchill, Melissa J., Gorry, Paul R.
Publicado em 2013