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Ex Vivo Response to Histone Deacetylase (HDAC) Inhibitors of the HIV Long Terminal Repeat (LTR) Derived from HIV-Infected Patients on Antiretroviral Therapy

Histone deacetylase inhibitors (HDACi) can induce human immunodeficiency virus (HIV) transcription from the HIV long terminal repeat (LTR). However, ex vivo and in vivo responses to HDACi are variable and the activity of HDACi in cells other than T-cells have not been well characterised. Here, we de...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lu, Hao K., Gray, Lachlan R., Wightman, Fiona, Ellenberg, Paula, Khoury, Gabriela, Cheng, Wan-Jung, Mota, Talia M., Wesselingh, Steve, Gorry, Paul R., Cameron, Paul U., Churchill, Melissa J., Lewin, Sharon R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4237424/
https://ncbi.nlm.nih.gov/pubmed/25409334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113341
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