Reduced Basal Transcriptional Activity of Central Nervous System-Derived HIV Type 1 Long Terminal Repeats

New evidence indicates that astrocytes of the central nervous system (CNS) are extensively infected with human immunodeficiency virus type 1 (HIV-1) in vivo. Although no new virus is produced, this nonproductive or restricted infection contributes to the pathogenesis of HIV-associated dementia (HAD)...

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Detalhes bibliográficos
Main Authors: Gray, Lachlan R., Cowley, Daniel, Crespan, Emma, Welsh, Casey, Mackenzie, Charlene, Wesselingh, Steve L., Gorry, Paul R., Churchill, Melissa J.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
Assuntos:
Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3552182/
https://ncbi.nlm.nih.gov/pubmed/22924643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2012.0138
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