An Integrated Approach for Identification and Target Validation of Antifungal Compounds Active against Erg11p

Por Hoepfner, Dominic, Karkare, Shantanu, Helliwell, Stephen B., Pfeifer, Martin, Trunzer, Markus, De Bonnechose, Sophie, Zimmerlin, Alfred, Tao, Jianshi, Richie, Daryl, Hofmann, Andreas, Reinker, Stefan, Frederiksen, Mathias, Movva, N. Rao, Porter, Jeffrey A., Ryder, Neil S., Parker, Christian N.
Publicado em 2012

FR171456 is a specific inhibitor of mammalian NSDHL and yeast Erg26p

Por Helliwell, Stephen B., Karkare, Shantanu, Bergdoll, Marc, Rahier, Alain, Leighton-Davis, Juliet R., Fioretto, Celine, Aust, Thomas, Filipuzzi, Ireos, Frederiksen, Mathias, Gounarides, John, Hoepfner, Dominic, Hofmann, Andreas, Imbert, Pierre-Eloi, Jeker, Rolf, Knochenmuss, Richard, Krastel, Philipp, Margerit, Anais, Memmert, Klaus, Miault, Charlotte V., Rao Movva, N., Muller, Alban, Naegeli, Hans-Ulrich, Oberer, Lukas, Prindle, Vivian, Riedl, Ralph, Schuierer, Sven, Sexton, Jessica A., Tao, Jianshi, Wagner, Trixie, Yin, Hong, Zhang, Juan, Roggo, Silvio, Reinker, Stefan, Parker, Christian N.
Publicado no Nat Commun (2015)

The promise and peril of chemical probes

Por Arrowsmith, Cheryl H, Audia, James E, Austin, Christopher, Baell, Jonathan, Bennett, Jonathan, Blagg, Julian, Bountra, Chas, Brennan, Paul E, Brown, Peter J, Bunnage, Mark E, Buser-Doepner, Carolyn, Campbell, Robert M, Carter, Adrian J, Cohen, Philip, Copeland, Robert A, Cravatt, Ben, Dahlin, Jayme L, Dhanak, Dashyant, Edwards, Aled M, Frederiksen, Mathias, Frye, Stephen V, Gray, Nathanael, Grimshaw, Charles E, Hepworth, David, Howe, Trevor, Huber, Kilian V M, Jin, Jian, Knapp, Stefan, Kotz, Joanne D, Kruger, Ryan G, Lowe, Derek, Mader, Mary M, Marsden, Brian, Mueller-Fahrnow, Anke, Müller, Susanne, O'Hagan, Ronan C, Overington, John P, Owen, Dafydd R, Rosenberg, Saul H, Ross, Ruth, Roth, Bryan, Schapira, Matthieu, Schreiber, Stuart L, Shoichet, Brian, Sundström, Michael, Superti-Furga, Giulio, Taunton, Jack, Toledo-Sherman, Leticia, Walpole, Chris, Walters, Michael A, Willson, Timothy M, Workman, Paul, Young, Robert N, Zuercher, William J
Publicado no Nat Chem Biol (2015)