Targeting Methionine Synthase in a Fungal Pathogen Causes a Metabolic Imbalance That Impacts Cell Energetics, Growth, and Virulence

le Scott, Jennifer, Sueiro-Olivares, Monica, Thornton, Benjamin P., Owens, Rebecca A., Muhamadali, Howbeer, Fortune-Grant, Rachael, Thomson, Darren, Thomas, Riba, Hollywood, Katherine, Doyle, Sean, Goodacre, Royston, Tabernero, Lydia, Bignell, Elaine, Amich, Jorge
Foilsithe in mBio (2020)

Fungal and host protein persulfidation are functionally correlated and modulate both virulence and antifungal response

le Sueiro-Olivares, Monica, Scott, Jennifer, Gago, Sara, Petrovic, Dunja, Kouroussis, Emilia, Zivanovic, Jasmina, Yu, Yidong, Strobel, Marlene, Cunha, Cristina, Thomson, Darren, Fortune-Grant, Rachael, Thusek, Sina, Bowyer, Paul, Beilhack, Andreas, Carvalho, Agostinho, Bignell, Elaine, Filipovic, Milos R., Amich, Jorge
Foilsithe in PLoS Biol (2021)

Differential sensitivity of gastric and small intestinal muscles to inducible knockdown of anoctamin 1 and the effects on gastrointestinal motility

le Hwang, Sung Jin, Pardo, David M., Zheng, Haifeng, Bayguinov, Yulia, Blair, Peter J., Fortune‐Grant, Rachael, Cook, Robert S., Hennig, Grant W., Shonnard, Matthew C., Grainger, Nathan, Peri, Lauren E., Verma, Sonali Deep, Rock, Jason, Sanders, Kenton M., Ward, Sean M.
Foilsithe in J Physiol (2019)

The negative cofactor 2 complex is a key regulator of drug resistance in Aspergillus fumigatus

le Furukawa, Takanori, van Rhijn, Norman, Fraczek, Marcin, Gsaller, Fabio, Davies, Emma, Carr, Paul, Gago, Sara, Fortune-Grant, Rachael, Rahman, Sayema, Gilsenan, Jane Mabey, Houlder, Emma, Kowalski, Caitlin H., Raj, Shriya, Paul, Sanjoy, Cook, Peter, Parker, Josie E., Kelly, Steve, Cramer, Robert A., Latgé, Jean-Paul, Moye-Rowley, Scott, Bignell, Elaine, Bowyer, Paul, Bromley, Michael J.
Foilsithe in Nat Commun (2020)