Antioxidant macromolecules in the epithelial lining fluid of the normal human lower respiratory tract.

Por Cantin, A M, Fells, G A, Hubbard, R C, Crystal, R G
Publicado em 1990

Role of connective tissue proteases in the pathogenesis of chronic inflammatory lung disease.

Por Gadek, J E, Fells, G A, Zimmerman, R L, Crystal, R G
Publicado em 1984

Characterization of the gene and protein of the common alpha 1-antitrypsin normal M2 allele.

Por Nukiwa, T, Brantly, M L, Ogushi, F, Fells, G A, Crystal, R G
Publicado em 1988

Risk factors for emphysema. Cigarette smoking is associated with a reduction in the association rate constant of lung alpha 1-antitrypsin for neutrophil elastase.

Por Ogushi, F, Hubbard, R C, Vogelmeier, C, Fells, G A, Crystal, R G
Publicado em 1991

Z-type alpha 1-antitrypsin is less competent than M1-type alpha 1-antitrypsin as an inhibitor of neutrophil elastase.

Por Ogushi, F, Fells, G A, Hubbard, R C, Straus, S D, Crystal, R G
Publicado em 1987

Antielastases of the human alveolar structures. Implications for the protease-antiprotease theory of emphysema.

Por Gadek, J E, Fells, G A, Zimmerman, R L, Rennard, S I, Crystal, R G
Publicado em 1981

Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis.

Por Cantin, A M, North, S L, Fells, G A, Hubbard, R C, Crystal, R G
Publicado em 1987

Alveolar macrophages release an insulin-like growth factor I-type molecule.

Por Rom, W N, Basset, P, Fells, G A, Nukiwa, T, Trapnell, B C, Crysal, R G
Publicado em 1988

Eosinophil-mediated injury to lung parenchymal cells and interstitial matrix. A possible role for eosinophils in chronic inflammatory disorders of the lower respiratory tract.

Por Davis, W B, Fells, G A, Sun, X H, Gadek, J E, Venet, A, Crystal, R G
Publicado em 1984

Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neut...

Por Hubbard, R C, Ogushi, F, Fells, G A, Cantin, A M, Jallat, S, Courtney, M, Crystal, R G
Publicado em 1987

Anti-neutrophil elastase defense of the normal human respiratory epithelial surface provided by the secretory leukoprotease inhibitor.

Por Vogelmeier, C, Hubbard, R C, Fells, G A, Schnebli, H P, Thompson, R C, Fritz, H, Crystal, R G
Publicado em 1991

Production of glycosylated physiologically "normal" human alpha 1-antitrypsin by mouse fibroblasts modified by insertion of a human alpha 1-antitrypsin cDNA using a retroviral vect...

Por Garver, R I, Chytil, A, Karlsson, S, Fells, G A, Brantly, M L, Courtney, M, Kantoff, P W, Nienhuis, A W, Anderson, W F, Crystal, R G
Publicado em 1987