Probing Mechanisms of CYP3A Time-Dependent Inhibition Using a Truncated Model System

Por Wang, Xiaojing, Sun, Minghua, New, Connie, Nam, Spencer, Blackaby, Wesley P., Hodges, Alastair J., Nash, David, Matteucci, Mizio, Lyssikatos, Joseph P., Fan, Peter W., Tay, Suzanne, Chang, Jae H.
Publicado no ACS Med Chem Lett (2015)

Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elim...

Por Fan, Peter W., Chen, Jacob Z., Jaochico, M. Allan, La, Hank, Liu, Ning, Mulder, Teresa, Cass, Robert T., Durk, Matthew, Messick, Kirsten, Valle, Nicole, Liu, Shannon, Lee, Wendy, Crawford, James J., Rudolph, Joachim, Murray, Lesley J., Khojasteh, S. Cyrus, Wright, Matthew
Publicado no Drug Metab Lett (2016)

NF-κB inducing kinase is a therapeutic target for systemic lupus erythematosus

Por Brightbill, Hans D., Suto, Eric, Blaquiere, Nicole, Ramamoorthi, Nandhini, Sujatha-Bhaskar, Swathi, Gogol, Emily B., Castanedo, Georgette M., Jackson, Benjamin T., Kwon, Youngsu C., Haller, Susan, Lesch, Justin, Bents, Karin, Everett, Christine, Kohli, Pawan Bir, Linge, Sandra, Christian, Laura, Barrett, Kathy, Jaochico, Allan, Berezhkovskiy, Leonid M., Fan, Peter W., Modrusan, Zora, Veliz, Kelli, Townsend, Michael J., DeVoss, Jason, Johnson, Adam R., Godemann, Robert, Lee, Wyne P., Austin, Cary D., McKenzie, Brent S., Hackney, Jason A., Crawford, James J., Staben, Steven T., Alaoui Ismaili, Moulay H., Wu, Lawren C., Ghilardi, Nico
Publicado no Nat Commun (2018)