The Adverse Outcome Pathway: A Multifaceted Framework Supporting 21(st) Century Toxicology

por Ankley, Gerald T., Edwards, Stephen W.
Publicado en Curr Opin Toxicol (2018)

Identification and Prioritization of Relationships between Environmental Stressors and Adverse Human Health Impacts

por Bell, Shannon M., Edwards, Stephen W.
Publicado en Environ Health Perspect (2015)

AOP-DB: A database resource for the exploration of Adverse Outcome Pathways through integrated association networks

por Pittman, Maureen E., Edwards, Stephen W., Ives, Cataia, Mortensen, Holly M.
Publicado en Toxicol Appl Pharmacol (2018)

A case study application of the Aggregate Exposure Pathway (AEP) and Adverse Outcome Pathway (AOP) frameworks to facilitate the integration of human health and ecological endpoints...

por Hines, David E., Edwards, Stephen W., Conolly, Rory B., Jarabek, Annie M.
Publicado en Environ Sci Technol (2017)

Cis-regulatory variations: A study of SNPs around genes showing cis-linkage in segregating mouse populations

por GuhaThakurta, Debraj, Xie, Tao, Anand, Manish, Edwards, Stephen W, Li, Guoya, Wang, Susanna S, Schadt, Eric E
Publicado 2006

Advancing the Next Generation of Health Risk Assessment

por Cote, Ila, Anastas, Paul T., Birnbaum, Linda S., Clark, Rebecca M., Dix, David J., Edwards, Stephen W., Preuss, Peter W.
Publicado 2012

Transcriptional Modulation of the ERK1/2 MAPK and NF-κB Pathways in Human Urothelial Cells After Trivalent Arsenical Exposure: Implications for Urinary Bladder Cancer

por Bailey, Kathryn A., Wallace, Kathleen, Smeester, Lisa, Thai, Sheau-Fung, Wolf, Douglas C., Edwards, Stephen W., Fry, Rebecca C.
Publicado 2012

Differentiating Pathway-Specific From Nonspecific Effects in High-Throughput Toxicity Data: A Foundation for Prioritizing Adverse Outcome Pathway Development

por Fay, Kellie A., Villeneuve, Daniel L., Swintek, Joe, Edwards, Stephen W., Nelms, Mark D., Blackwell, Brett R., Ankley, Gerald T.
Publicado en Toxicol Sci (2018)

Knowledge Organization Systems for Systematic Chemical Assessments

por Whaley, Paul, Edwards, Stephen W., Kraft, Andrew, Nyhan, Kate, Shapiro, Andrew, Watford, Sean, Wattam, Steve, Wolffe, Taylor, Angrish, Michelle
Publicado en Environ Health Perspect (2020)

Systems Biology and Biomarkers of Early Effects for Occupational Exposure Limit Setting

por DeBord, D. Gayle, Burgoon, Lyle, Edwards, Stephen W., Haber, Lynne T., Kanitz, M. Helen, Kuempel, Eileen, Thomas, Russell S., Yucesoy, Berran
Publicado en J Occup Environ Hyg (2015)

An Assessment of Environmental Health Measures in the Deepwater Horizon Research Consortia

por Pan, Huaqin, Edwards, Stephen W., Ives, Cataia, Covert, Hannah, Harville, Emily W., Lichtveld, Maureen Y., Wickliffe, Jeffrey K., Hamilton, Carol M.
Publicado en Curr Opin Toxicol (2019)

Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population

por Joubert, Bonnie R, Reif, David M, Edwards, Stephen W, Leiner, Kevin A, Hudgens, Edward E, Egeghy, Peter, Gallagher, Jane E, Hubal, Elaine Cohen
Publicado 2011

Decision tree-based method for integrating gene expression, demographic, and clinical data to determine disease endotypes

por Williams-DeVane, ClarLynda R, Reif, David M, Cohen Hubal, Elaine, Bushel, Pierre R, Hudgens, Edward E, Gallagher, Jane E, Edwards, Stephen W
Publicado en BMC Syst Biol (2013)

A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways

por Phillips, Martin B., Leonard, Jeremy A., Grulke, Christopher M., Chang, Daniel T., Edwards, Stephen W., Brooks, Raina, Goldsmith, Michael-Rock, El-Masri, Hisham, Tan, Yu-Mei
Publicado en Environ Health Perspect (2015)

Data-Driven Asthma Endotypes Defined from Blood Biomarker and Gene Expression Data

por George, Barbara Jane, Reif, David M., Gallagher, Jane E., Williams-DeVane, ClarLynda R., Heidenfelder, Brooke L., Hudgens, Edward E., Jones, Wendell, Neas, Lucas, Hubal, Elaine A. Cohen, Edwards, Stephen W.
Publicado en PLoS One (2015)

Uses of NHANES Biomarker Data for Chemical Risk Assessment: Trends, Challenges, and Opportunities

por Sobus, Jon R., DeWoskin, Robert S., Tan, Yu-Mei, Pleil, Joachim D., Phillips, Martin Blake, George, Barbara Jane, Christensen, Krista, Schreinemachers, Dina M., Williams, Marc A., Hubal, Elaine A. Cohen, Edwards, Stephen W.
Publicado en Environ Health Perspect (2015)

Completing the Link between Exposure Science and Toxicology for Improved Environmental Health Decision Making: The Aggregate Exposure Pathway Framework

por Teeguarden, Justin. G., Tan, Yu-Mei, Edwards, Stephen W., Leonard, Jeremy A., Anderson, Kim A., Corley, Richard A., Harding, Anna K, Kile, Molly L., Simonich, Staci M, Stone, David, Tanguay, Robert L., Waters, Katrina M., Harper, Stacey L., Williams, David E.
Publicado en Environ Sci Technol (2016)

A comprehensive transcript index of the human genome generated using microarrays and computational approaches

por Schadt, Eric E, Edwards, Stephen W, GuhaThakurta, Debraj, Holder, Dan, Ying, Lisa, Svetnik, Vladimir, Leonardson, Amy, Hart, Kyle W, Russell, Archie, Li, Guoya, Cavet, Guy, Castle, John, McDonagh, Paul, Kan, Zhengyan, Chen, Ronghua, Kasarskis, Andrew, Margarint, Mihai, Caceres, Ramon M, Johnson, Jason M, Armour, Christopher D, Garrett-Engele, Philip W, Tsinoremas, Nicholas F, Shoemaker, Daniel D
Publicado 2004

The Next Generation of Risk Assessment Multi-Year Study—Highlights of Findings, Applications to Risk Assessment, and Future Directions

por Cote, Ila, Andersen, Melvin E., Ankley, Gerald T., Barone, Stanley, Birnbaum, Linda S., Boekelheide, Kim, Bois, Frederic Y., Burgoon, Lyle D., Chiu, Weihsueh A., Crawford-Brown, Douglas, Crofton, Kevin M., DeVito, Michael, Devlin, Robert B., Edwards, Stephen W., Guyton, Kathryn Z., Hattis, Dale, Judson, Richard S., Knight, Derek, Krewski, Daniel, Lambert, Jason, Maull, Elizabeth Anne, Mendrick, Donna, Paoli, Gregory M., Patel, Chirag Jagdish, Perkins, Edward J., Poje, Gerald, Portier, Christopher J., Rusyn, Ivan, Schulte, Paul A., Simeonov, Anton, Smith, Martyn T., Thayer, Kristina A., Thomas, Russell S., Thomas, Reuben, Tice, Raymond R., Vandenberg, John J., Villeneuve, Daniel L., Wesselkamper, Scott, Whelan, Maurice, Whittaker, Christine, White, Ronald, Xia, Menghang, Yauk, Carole, Zeise, Lauren, Zhao, Jay, DeWoskin, Robert S.
Publicado en Environ Health Perspect (2016)