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A Workflow to Investigate Exposure and Pharmacokinetic Influences on High-Throughput in Vitro Chemical Screening Based on Adverse Outcome Pathways
BACKGROUND: Adverse outcome pathways (AOPs) link adverse effects in individuals or populations to a molecular initiating event (MIE) that can be quantified using in vitro methods. Practical application of AOPs in chemical-specific risk assessment requires incorporation of knowledge on exposure, alon...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Environ Health Perspect |
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| Κύριοι συγγραφείς: | , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Institute of Environmental Health Sciences
2015
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4710605/ https://ncbi.nlm.nih.gov/pubmed/25978103 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1409450 |
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