Pre-clinical efficacy and synergistic potential of the MDM2-p53 antagonists, Nutlin-3 and RG7388, as single agents and in combined treatment with cisplatin in ovarian cancer

Por Zanjirband, Maryam, Edmondson, Richard J., Lunec, John
Publicado no Oncotarget (2016)

Combination treatment with rucaparib (Rubraca) and MDM2 inhibitors, Nutlin-3 and RG7388, has synergistic and dose reduction potential in ovarian cancer

Por Zanjirband, Maryam, Curtin, Nicola, Edmondson, Richard J., Lunec, John
Publicado no Oncotarget (2017)

DNA damage repair in ovarian cancer: unlocking the heterogeneity

Por Gee, Mary Ellen, Faraahi, Zahra, McCormick, Aiste, Edmondson, Richard J.
Publicado no J Ovarian Res (2018)

Engineering microrobots for targeted cancer therapies from a medical perspective

Por Schmidt, Christine K., Medina-Sánchez, Mariana, Edmondson, Richard J., Schmidt, Oliver G.
Publicado no Nat Commun (2020)

Epithelial ovarian cancer risk: A review of the current genetic landscape

Por Flaum, Nicola, Crosbie, Emma J., Edmondson, Richard J., Smith, Miriam J., Evans, Dafydd G.
Publicado no Clin Genet (2019)

First-Line Management of Advanced High-Grade Serous Ovarian Cancer

Por Mahmood, Reem D., Morgan, Robert D., Edmondson, Richard J., Clamp, Andrew R., Jayson, Gordon C.
Publicado no Curr Oncol Rep (2020)

PARP inhibitors in platinum-sensitive high-grade serous ovarian cancer

Por Morgan, Robert D., Clamp, Andrew R., Evans, D. Gareth R., Edmondson, Richard J., Jayson, Gordon C.
Publicado no Cancer Chemother Pharmacol (2018)

Interventions for weight reduction in obesity to improve survival in women with endometrial cancer

Por Kitson, Sarah, Ryan, Neil, MacKintosh, Michelle L, Edmondson, Richard, Duffy, James MN, Crosbie, Emma J
Publicado no Cochrane Database Syst Rev (2018)

A Prospective Study to Identify Rates of SARS-CoV-2 Virus in the Peritoneum and Lower Genital Tract of Patients Having Surgery: An Observational Study

Por Jones, Dominique, Faluyi, David, Hamilton, Sarah, Stylianides, Nicholas, Ma, Ken, Duff, Sarah, Machin, Nicholas, Edmondson, Richard J.
Publicado no J Minim Invasive Gynecol (2021)

Factors determining ultra-short-term survival and the commencement of active treatment in high-grade serous ovarian cancer: a case comparison study

Por Hawarden, Amy, Russell, Bryn, Gee, Mary Ellen, Skayali, Fatima, Clamp, Andrew, Crosbie, Emma Jayne, Edmondson, Richard John
Publicado no BMC Cancer (2021)

Ex vivo expanded tumour-infiltrating lymphocytes from ovarian cancer patients release anti-tumour cytokines in response to autologous primary ovarian cancer cells

Por Owens, Gemma L., Price, Marcus J., Cheadle, Eleanor J., Hawkins, Robert E., Gilham, David E., Edmondson, Richard J.
Publicado no Cancer Immunol Immunother (2018)

The unrecognized burden of cardiovascular risk factors in women newly diagnosed with endometrial cancer: A prospective case control study

Por Kitson, Sarah J., Lindsay, Jennifer, Sivalingam, Vanitha N., Lunt, Mark, Ryan, Neil A.J., Edmondson, Richard J., Rutter, Martin K., Crosbie, Emma J.
Publicado no Gynecol Oncol (2018)

Ovarian Cancers Harbour Defects in Non-Homologous End Joining Resulting in Resistance to Rucaparib

Por McCormick, Aiste, Donoghue, Peter, Dixon, Michelle, O’Sullivan, Richard, O’Donnell, Rachel L, Murray, James, Kaufmann, Angelika, Curtin, Nicola J, Edmondson, Richard J
Publicado no Clin Cancer Res (2016)

Preclinical Assessment of CAR T-Cell Therapy Targeting the Tumor Antigen 5T4 in Ovarian Cancer

Por Owens, Gemma L., Sheard, Victoria E., Kalaitsidou, Milena, Blount, Daniel, Lad, Yatish, Cheadle, Eleanor J., Edmondson, Richard J., Kooner, Gurdeep, Gilham, David E., Harrop, Richard
Publicado no J Immunother (2018)

BRCA1 and BRCA2 pathogenic variant carriers and endometrial cancer risk: A cohort study

Por Kitson, Sarah J., Bafligil, Cemsel, Ryan, Neil A.J., Lalloo, Fiona, Woodward, Emma R., Clayton, Richard D., Edmondson, Richard J., Bolton, James, Crosbie, Emma J., Evans, D. Gareth
Publicado no Eur J Cancer (2020)

The Use of Ovarian Cancer Cells from Patients Undergoing Surgery to Generate Primary Cultures Capable of Undergoing Functional Analysis

Por O′Donnell, Rachel L., McCormick, Aiste, Mukhopadhyay, Asima, Woodhouse, Laura C., Moat, Madeleine, Grundy, Anna, Dixon, Michelle, Kaufman, Angelika, Soohoo, San, Elattar, Ahmed, Curtin, Nicola J., Edmondson, Richard J.
Publicado em 2014

Functional characterisation of a novel ovarian cancer cell line, NUOC-1

Por McCormick, Aiste, Earp, Eleanor, Elliot, Katherine, Cuthbert, Gavin, O'Donnell, Rachel, Wilson, Brian T., Sutton, Ruth, Leeson, Charlotte, Thomas, Huw D., Blair, Helen, Fordham, Sarah, Lunec, John, Allan, James, Edmondson, Richard J.
Publicado no Oncotarget (2017)

Specialist oncological surgery for removal of the ovaries and fallopian tubes in BRCA1 and BRCA2 pathogenic variant carriers may reduce primary peritoneal cancer risk to very low l...

Por Crosbie, Emma J., Flaum, Nicola, Harkness, Elaine F., Clayton, Richard D., Holland, Cathrine, Martin‐Hirsch, Pierre, Wood, Nick, Keating, Patrick, Woodward, Emma R., Lalloo, Fiona, Donnai, Paul, Edmondson, Richard J., Evans, D. Gareth
Publicado no Int J Cancer (2020)

Common cancer-associated imbalances in the DNA damage response confer sensitivity to single agent ATR inhibition

Por Middleton, Fiona K., Patterson, Miranda J., Elstob, Claire J., Fordham, Sarah, Herriott, Ashleigh, Wade, Mark A., McCormick, Aiste, Edmondson, Richard, May, Felicity E.B., Allan, James M., Pollard, John R., Curtin, Nicola J.
Publicado no Oncotarget (2015)

High‐resolution imaging for the detection and characterisation of circulating tumour cells from patients with oesophageal, hepatocellular, thyroid and ovarian cancers

Por Dent, Barry M., Ogle, Laura F., O'Donnell, Rachel L., Hayes, Nicholas, Malik, Ujjal, Curtin, Nicola J., Boddy, Alan V., Plummer, E. Ruth, Edmondson, Richard J., Reeves, Helen L., May, Felicity E.B., Jamieson, David
Publicado no Int J Cancer (2015)