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Preclinical Assessment of CAR T-Cell Therapy Targeting the Tumor Antigen 5T4 in Ovarian Cancer

Chimeric antigen receptor (CAR) T cells represent a novel targeted approach to overcome both quantitative and qualitative shortfalls of the host immune system relating to the detection and subsequent destruction of tumors. The identification of antigens expressed specifically on the surface of tumor...

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Detalhes bibliográficos
Publicado no:J Immunother
Main Authors: Owens, Gemma L., Sheard, Victoria E., Kalaitsidou, Milena, Blount, Daniel, Lad, Yatish, Cheadle, Eleanor J., Edmondson, Richard J., Kooner, Gurdeep, Gilham, David E., Harrop, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5895166/
https://ncbi.nlm.nih.gov/pubmed/29239915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0000000000000203
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