Multi-target mode of action of a Clerodane-type diterpenoid from Polyalthia longifolia targeting African trypanosomes

di Ebiloma, Godwin U., Katsoulis, Evangelos, Igoli, John O., Gray, Alexander I., De Koning, Harry P.
Pubblicato in Sci Rep (2018)

9-(2′-Deoxy-2′-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance

di Ranjbarian, Farahnaz, Vodnala, Munender, Alzahrani, Khalid J. H., Ebiloma, Godwin U., de Koning, Harry P., Hofer, Anders
Pubblicato in Antimicrob Agents Chemother (2017)

The Strong Anti-Kinetoplastid Properties of Bee Propolis: Composition and Identification of the Active Agents and Their Biochemical Targets

di Ebiloma, Godwin U., Ichoron, Nahandoo, Siheri, Weam, Watson, David G., Igoli, John O., De Koning, Harry P.
Pubblicato in Molecules (2020)

Sustainable Elimination (Zero Cases) of Sleeping Sickness: How Far Are We from Achieving This Goal?

di Akazue, Pearl Ihuoma, Ebiloma, Godwin U., Ajibola, Olumide, Isaac, Clement, Onyekwelu, Kenechukwu, Ezeh, Charles O., Eze, Anthonius Anayochukwu
Pubblicato in Pathogens (2019)

A Review of the Antimalarial, Antitrypanosomal, and Antileishmanial Activities of Natural Compounds Isolated From Nigerian Flora

di Ungogo, Marzuq A., Ebiloma, Godwin U., Ichoron, Nahandoo, Igoli, John O., de Koning, Harry P., Balogun, Emmanuel O.
Pubblicato in Front Chem (2020)

Design and Synthesis of a Series of Truncated Neplanocin Fleximers

di Zimmermann, Sarah C., O’Neill, Elizaveta, Ebiloma, Godwin U., Wallace, Lynsey J. M., De Koning, Harry P., Seley-Radtke, Katherine L.
Pubblicato in Molecules (2014)

Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs

di Nnadi, Charles O., Ebiloma, Godwin U., Black, Jennifer A., Nwodo, Ngozi J., Lemgruber, Leandro, Schmidt, Thomas J., de Koning, Harry P.
Pubblicato in Molecules (2019)

European propolis is highly active against trypanosomatids including Crithidia fasciculata

di Alotaibi, Abdullah, Ebiloma, Godwin U., Williams, Roderick, Alenezi, Samya, Donachie, Anne-Marie, Guillaume, Selome, Igoli, John O., Fearnley, James, de Koning, Harry P., Watson, David G.
Pubblicato in Sci Rep (2019)

Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy

di Rodenko, Boris, Wanner, Martin J., Alkhaldi, Abdulsalam A. M., Ebiloma, Godwin U., Barnes, Rebecca L., Kaiser, Marcel, Brun, Reto, McCulloch, Richard, Koomen, Gerrit-Jan, de Koning, Harry P.
Pubblicato in Antimicrob Agents Chemother (2015)

Functional and structural analysis of AT-specific minor groove binders that disrupt DNA–protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast

di Millan, Cinthia R., Acosta-Reyes, Francisco J., Lagartera, Laura, Ebiloma, Godwin U., Lemgruber, Leandro, Nué Martínez, J. Jonathan, Saperas, Núria, Dardonville, Christophe, de Koning, Harry P., Campos, J. Lourdes
Pubblicato in Nucleic Acids Res (2017)

Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria

di Ajibaye, Olusola, Osuntoki, Akinniyi A., Balogun, Emmanuel O., Olukosi, Yetunde A., Iwalokun, Bamidele A., Oyebola, Kolapo M., Hikosaka, Kenji, Watanabe, Yoh-ichi, Ebiloma, Godwin U., Kita, Kiyoshi, Amambua-Ngwa, Alfred
Pubblicato in Malar J (2020)

The Chemical Characterization of Nigerian Propolis samples and Their Activity Against Trypanosoma brucei

di Omar, Ruwida, Igoli, John O., Zhang, Tong, Gray, Alexander I., Ebiloma, Godwin U., Clements, Carol J., Fearnley, James, Edrada Ebel, RuAngeli, Paget, Tim, de Koning, Harry P., Watson, David G.
Pubblicato in Sci Rep (2017)

Activity of Compounds from Temperate Propolis against Trypanosoma brucei and Leishmania mexicana

di Alotaibi, Adullah, Ebiloma, Godwin U., Williams, Roderick, Alfayez, Ibrahim A., Natto, Manal J., Alenezi, Sameah, Siheri, Weam, AlQarni, Malik, Igoli, John O., Fearnley, James, De Koning, Harry P., Watson, David G.
Pubblicato in Molecules (2021)

Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)‐Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei...

di Cerone, Michela, Uliassi, Elisa, Prati, Federica, Ebiloma, Godwin U., Lemgruber, Leandro, Bergamini, Christian, Watson, David G., de A. M. Ferreira, Thais, Roth Cardoso, Gabriella Simões Heyn, Soares Romeiro, Luiz A., de Koning, Harry P., Bolognesi, Maria Laura
Pubblicato in ChemMedChem (2019)

SAR of 4-Alkoxybenzoic Acid Inhibitors of the Trypanosome Alternative Oxidase

di Meco-Navas, Alejandro, Ebiloma, Godwin U., Martín-Domínguez, Ana, Martínez-Benayas, Irene, Cueto-Díaz, Eduardo J., Alhejely, Amani Saud, Balogun, Emmanuel O., Saito, Machi, Matsui, Miho, Arai, Natsumi, Shiba, Tomoo, Harada, Shigeharu, de Koning, Harry P., Dardonville, Christophe
Pubblicato in ACS Med Chem Lett (2018)

Isolation of a Novel Flavanonol and an Alkylresorcinol with Highly Potent Anti-Trypanosomal Activity from Libyan Propolis

di Siheri, Weam, Ebiloma, Godwin U., Igoli, John O., Gray, Alexander I., Biddau, Marco, Akrachalanont, Pilaslak, Alenezi, Samya, Alwashih, Mohammad A., Edrada-Ebel, RuAngelie, Muller, Sylke, Lawrence, Catherine E., Fearnley, James, Watson, David G., De Koning, Harry P.
Pubblicato in Molecules (2019)