Multi-target mode of action of a Clerodane-type diterpenoid from Polyalthia longifolia targeting African trypanosomes

gan Ebiloma, Godwin U., Katsoulis, Evangelos, Igoli, John O., Gray, Alexander I., De Koning, Harry P.
Cyhoeddwyd yn Sci Rep (2018)

9-(2′-Deoxy-2′-Fluoro-β-d-Arabinofuranosyl) Adenine Is a Potent Antitrypanosomal Adenosine Analogue That Circumvents Transport-Related Drug Resistance

gan Ranjbarian, Farahnaz, Vodnala, Munender, Alzahrani, Khalid J. H., Ebiloma, Godwin U., de Koning, Harry P., Hofer, Anders
Cyhoeddwyd yn Antimicrob Agents Chemother (2017)

The Strong Anti-Kinetoplastid Properties of Bee Propolis: Composition and Identification of the Active Agents and Their Biochemical Targets

gan Ebiloma, Godwin U., Ichoron, Nahandoo, Siheri, Weam, Watson, David G., Igoli, John O., De Koning, Harry P.
Cyhoeddwyd yn Molecules (2020)

Sustainable Elimination (Zero Cases) of Sleeping Sickness: How Far Are We from Achieving This Goal?

gan Akazue, Pearl Ihuoma, Ebiloma, Godwin U., Ajibola, Olumide, Isaac, Clement, Onyekwelu, Kenechukwu, Ezeh, Charles O., Eze, Anthonius Anayochukwu
Cyhoeddwyd yn Pathogens (2019)

A Review of the Antimalarial, Antitrypanosomal, and Antileishmanial Activities of Natural Compounds Isolated From Nigerian Flora

gan Ungogo, Marzuq A., Ebiloma, Godwin U., Ichoron, Nahandoo, Igoli, John O., de Koning, Harry P., Balogun, Emmanuel O.
Cyhoeddwyd yn Front Chem (2020)

Design and Synthesis of a Series of Truncated Neplanocin Fleximers

gan Zimmermann, Sarah C., O’Neill, Elizaveta, Ebiloma, Godwin U., Wallace, Lynsey J. M., De Koning, Harry P., Seley-Radtke, Katherine L.
Cyhoeddwyd yn Molecules (2014)

Potent Antitrypanosomal Activities of 3-Aminosteroids against African Trypanosomes: Investigation of Cellular Effects and of Cross-Resistance with Existing Drugs

gan Nnadi, Charles O., Ebiloma, Godwin U., Black, Jennifer A., Nwodo, Ngozi J., Lemgruber, Leandro, Schmidt, Thomas J., de Koning, Harry P.
Cyhoeddwyd yn Molecules (2019)

European propolis is highly active against trypanosomatids including Crithidia fasciculata

gan Alotaibi, Abdullah, Ebiloma, Godwin U., Williams, Roderick, Alenezi, Samya, Donachie, Anne-Marie, Guillaume, Selome, Igoli, John O., Fearnley, James, de Koning, Harry P., Watson, David G.
Cyhoeddwyd yn Sci Rep (2019)

Targeting the Parasite's DNA with Methyltriazenyl Purine Analogs Is a Safe, Selective, and Efficacious Antitrypanosomal Strategy

gan Rodenko, Boris, Wanner, Martin J., Alkhaldi, Abdulsalam A. M., Ebiloma, Godwin U., Barnes, Rebecca L., Kaiser, Marcel, Brun, Reto, McCulloch, Richard, Koomen, Gerrit-Jan, de Koning, Harry P.
Cyhoeddwyd yn Antimicrob Agents Chemother (2015)

Functional and structural analysis of AT-specific minor groove binders that disrupt DNA–protein interactions and cause disintegration of the Trypanosoma brucei kinetoplast

gan Millan, Cinthia R., Acosta-Reyes, Francisco J., Lagartera, Laura, Ebiloma, Godwin U., Lemgruber, Leandro, Nué Martínez, J. Jonathan, Saperas, Núria, Dardonville, Christophe, de Koning, Harry P., Campos, J. Lourdes
Cyhoeddwyd yn Nucleic Acids Res (2017)

Genetic polymorphisms in malaria vaccine candidate Plasmodium falciparum reticulocyte-binding protein homologue-5 among populations in Lagos, Nigeria

gan Ajibaye, Olusola, Osuntoki, Akinniyi A., Balogun, Emmanuel O., Olukosi, Yetunde A., Iwalokun, Bamidele A., Oyebola, Kolapo M., Hikosaka, Kenji, Watanabe, Yoh-ichi, Ebiloma, Godwin U., Kita, Kiyoshi, Amambua-Ngwa, Alfred
Cyhoeddwyd yn Malar J (2020)

The Chemical Characterization of Nigerian Propolis samples and Their Activity Against Trypanosoma brucei

gan Omar, Ruwida, Igoli, John O., Zhang, Tong, Gray, Alexander I., Ebiloma, Godwin U., Clements, Carol J., Fearnley, James, Edrada Ebel, RuAngeli, Paget, Tim, de Koning, Harry P., Watson, David G.
Cyhoeddwyd yn Sci Rep (2017)

Activity of Compounds from Temperate Propolis against Trypanosoma brucei and Leishmania mexicana

gan Alotaibi, Adullah, Ebiloma, Godwin U., Williams, Roderick, Alfayez, Ibrahim A., Natto, Manal J., Alenezi, Sameah, Siheri, Weam, AlQarni, Malik, Igoli, John O., Fearnley, James, De Koning, Harry P., Watson, David G.
Cyhoeddwyd yn Molecules (2021)

Discovery of Sustainable Drugs for Neglected Tropical Diseases: Cashew Nut Shell Liquid (CNSL)‐Based Hybrids Target Mitochondrial Function and ATP Production in Trypanosoma brucei...

gan Cerone, Michela, Uliassi, Elisa, Prati, Federica, Ebiloma, Godwin U., Lemgruber, Leandro, Bergamini, Christian, Watson, David G., de A. M. Ferreira, Thais, Roth Cardoso, Gabriella Simões Heyn, Soares Romeiro, Luiz A., de Koning, Harry P., Bolognesi, Maria Laura
Cyhoeddwyd yn ChemMedChem (2019)

SAR of 4-Alkoxybenzoic Acid Inhibitors of the Trypanosome Alternative Oxidase

gan Meco-Navas, Alejandro, Ebiloma, Godwin U., Martín-Domínguez, Ana, Martínez-Benayas, Irene, Cueto-Díaz, Eduardo J., Alhejely, Amani Saud, Balogun, Emmanuel O., Saito, Machi, Matsui, Miho, Arai, Natsumi, Shiba, Tomoo, Harada, Shigeharu, de Koning, Harry P., Dardonville, Christophe
Cyhoeddwyd yn ACS Med Chem Lett (2018)

Isolation of a Novel Flavanonol and an Alkylresorcinol with Highly Potent Anti-Trypanosomal Activity from Libyan Propolis

gan Siheri, Weam, Ebiloma, Godwin U., Igoli, John O., Gray, Alexander I., Biddau, Marco, Akrachalanont, Pilaslak, Alenezi, Samya, Alwashih, Mohammad A., Edrada-Ebel, RuAngelie, Muller, Sylke, Lawrence, Catherine E., Fearnley, James, Watson, David G., De Koning, Harry P.
Cyhoeddwyd yn Molecules (2019)