Transposon-based screens for cancer gene discovery in mouse models

Por Dupuy, Adam J.
Publicado em 2010

Insertional mutagenesis strategies in cancer genetics

Por Dupuy, Adam J., Largaespada, David A.
Publicado em 2011

Domesticated transposable element gene products in human cancer

Por Riordan, Jesse D, Dupuy, Adam J
Publicado em 2013

Conditional deletion of Sox17 reveals complex effects on uterine adenogenesis and function

Por Guimarães-Young, Amy, Neff, Traci, Dupuy, Adam J, Goodheart, Michael J
Publicado no Dev Biol (2016)

Adaptive immunity does not strongly suppress spontaneous tumors in a Sleeping Beauty model of cancer

Por Rogers, Laura M., Olivier, Alicia K., Meyerholz, David K., Dupuy, Adam J.
Publicado em 2013

A Hybrid Adenoviral Vector System Achieves Efficient Long-Term Gene Expression in the Liver via piggyBac Transposition

Por Smith, Ryan P., Riordan, Jesse D., Feddersen, Charlotte R., Dupuy, Adam J.
Publicado no Hum Gene Ther (2015)

Ectopic expression of Zmiz1 induces cutaneous squamous cell malignancies in a mouse model of cancer

Por Rogers, Laura M., Riordan, Jesse D., Swick, Brian L., Meyerholz, David K., Dupuy, Adam J.
Publicado em 2013

Keratoacanthoma Pathobiology in Mouse Models

Por Gibson-Corley, Katherine N., Rogers, Laura M., Goeken, Adam, Dupuy, Adam J., Meyerholz, David K.
Publicado em 2014

Novel Molecular and Computational Methods Improve the Accuracy of Insertion Site Analysis in Sleeping Beauty-Induced Tumors

Por Brett, Benjamin T., Berquam-Vrieze, Katherine E., Nannapaneni, Kishore, Huang, Jian, Scheetz, Todd E., Dupuy, Adam J.
Publicado em 2011

Transposon mutagenesis of the mouse germline.

Por Carlson, Corey M, Dupuy, Adam J, Fritz, Sabine, Roberg-Perez, Kevin J, Fletcher, Colin F, Largaespada, David A
Publicado em 2003

A Trp53(fl/fl)Pten(fl/fl) mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging

Por Buchakjian, Marisa R., Merritt, Nicole M., Moose, Devon L., Dupuy, Adam J., Tanas, Munir R., Henry, Michael D.
Publicado no PLoS One (2017)

The Stress-Regulated Transcription Factor CHOP Promotes Hepatic Inflammatory Gene Expression, Fibrosis, and Oncogenesis

Por DeZwaan-McCabe, Diane, Riordan, Jesse D., Arensdorf, Angela M., Icardi, Michael S., Dupuy, Adam J., Rutkowski, D. Thomas
Publicado em 2013

Sequencing methods and datasets to improve functional interpretation of sleeping beauty mutagenesis screens

Por Riordan, Jesse D, Drury, Luke J, Smith, Ryan P, Brett, Benjamin T, Rogers, Laura M, Scheetz, Todd E, Dupuy, Adam J
Publicado no BMC Genomics (2014)

RNA sequencing of Sleeping Beauty transposon-induced tumors detects transposon-RNA fusions in forward genetic cancer screens

Por Temiz, Nuri A., Moriarity, Branden S., Wolf, Natalie K., Riordan, Jesse D., Dupuy, Adam J., Largaespada, David A., Sarver, Aaron L.
Publicado no Genome Res (2016)

MicroRNA-26b Represses Colon Cancer Cell Proliferation by Inhibiting Lymphoid Enhancer Factor 1 (LEF-1) Expression

Por Zhang, Zichao, Kim, KyoungHyun, Li, Xiao, Moreno, Myriam, Sharp, Thad, Goodheart, Micheal J., Safe, Stephen, Dupuy, Adam J., Amendt, Brad A.
Publicado em 2014

Cell-Internalization SELEX: Method for Identifying Cell-Internalizing RNA Aptamers for Delivering siRNAs to Target Cells

Por Thiel, William H., Thiel, Kristina W., Flenker, Katie S., Bair, Tom, Dupuy, Adam J., McNamara, James O., Miller, Francis J., Giangrande, Paloma H.
Publicado no Methods Mol Biol (2015)

A Sleeping Beauty screen reveals NF-kB activation in CLL mouse model

Por Zanesi, Nicola, Balatti, Veronica, Riordan, Jesse, Burch, Aaron, Rizzotto, Lara, Palamarchuk, Alexey, Cascione, Luciano, Lagana, Alessandro, Dupuy, Adam J., Croce, Carlo M., Pekarsky, Yuri
Publicado em 2013

A DNA transposon-based approach to validate oncogenic mutations in the mouse

Por Su, Qin, Prosser, Haydn M., Campos, Lia S., Ortiz, Mariaestela, Nakamura, Takuro, Warren, Madhuri, Dupuy, Adam J., Jenkins, Nancy A., Copeland, Neal G., Bradley, Allan, Liu, Pentao
Publicado em 2008

A comprehensive evaluation of Hippo pathway silencing in sarcomas

Por Merritt, Nicole M., Fullenkamp, Colleen A., Hall, Sarah L., Qian, Qining, Desai, Chandni, Thomason, Jon, Lambertz, Allyn M., Dupuy, Adam J., Darbro, Benjamin, Tanas, Munir R.
Publicado no Oncotarget (2018)

A modified Sleeping Beauty transposon system that can be used to model a wide variety of human cancers in mice

Por Dupuy, Adam J., Rogers, Laura M., Kim, Jinsil, Nannapaneni, Kishore, Starr, Timothy K., Liu, Pentao, Largaespada, David A., Scheetz, Todd E., Jenkins, Nancy A., Copeland, Neal G.
Publicado em 2009