Echinacoside Protects against 6-Hydroxydopamine-Induced Mitochondrial Dysfunction and Inflammatory Responses in PC12 Cells via Reducing ROS Production

Por Wang, Yue-Hua, Xuan, Zhao-Hong, Tian, Shuo, Du, Guan-Hua
Publicado no Evid Based Complement Alternat Med (2015)

Ramulus Cinnamomi extract attenuates neuroinflammatory responses via downregulating TLR4/MyD88 signaling pathway in BV2 cells

Por Yang, Huan, Cheng, Xiao, Yang, Ying-lin, Wang, Yue-hua, Du, Guan-hua
Publicado no Neural Regen Res (2017)

A novel acute anemia model for pharmacological research in mice by compelled acute exercise

Por Liu, Qing-shan, Wang, Jin-hua, Cui, Jian, Yang, Zhi-hong, Du, Guan-hua
Publicado em 2009

Esculin improves dyslipidemia, inflammation and renal damage in streptozotocin-induced diabetic rats

Por Wang, Yue-Hua, Liu, Yan-Hong, He, Guo-Rong, Lv, Yang, Du, Guan-Hua
Publicado no BMC Complement Altern Med (2015)

(1)H-NMR-Based Metabonomic Studies on the Anti-Depressant Effect of Genipin in the Chronic Unpredictable Mild Stress Rat Model

Por Tian, Jun-Sheng, Shi, Bi-Yun, Xiang, Huan, Gao, Shan, Qin, Xue-Mei, Du, Guan-Hua
Publicado em 2013

Pharmacokinetic study of salvianolic acid D after oral and intravenous administration in rats

Por Song, Junke, Zhang, Wen, Sun, Jialin, Xu, Xiaona, Zhang, Xue, Zhang, Li, Feng, Zhangying, Du, Guan-hua
Publicado no Acta Pharm Sin B (2015)

Uncovering the anticancer mechanism of Compound Kushen Injection against HCC by integrating quantitative analysis, network analysis and experimental validation

Por Gao, Li, Wang, Ke-xin, Zhou, Yu-zhi, Fang, Jian-song, Qin, Xue-mei, Du, Guan-hua
Publicado no Sci Rep (2018)

Protective Effect of Ultra Low Molecular Weight Heparin on Glutamate-Induced Apoptosis in Cortical Cells

Por Yu, Tian-Gui, Zhang, Qing-Zhu, Zhang, Zhi-Guo, Wang, Wei-Wei, Ji, Sheng-Li, Du, Guan-Hua
Publicado em 2008

Protective effects of the novel adenosine derivative WS0701 in a mouse model of posttraumatic stress disorder

Por Huang, Zhong-lin, Liu, Rui, Bai, Xiao-yu, Zhao, Gang, Song, Jun-ke, Wu, Song, Du, Guan-hua
Publicado em 2014

The Bioinformatic Analysis of the Dysregulated Genes and MicroRNAs in Entorhinal Cortex, Hippocampus, and Blood for Alzheimer's Disease

Por Pang, Xiaocong, Zhao, Ying, Wang, Jinhua, Zhou, Qimeng, Xu, Lvjie, Kang, De, Liu, Ai-Lin, Du, Guan-Hua
Publicado no Biomed Res Int (2017)

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulat...

Por Liu Rui, Wu Cai-xia, Zhou Dan, Yang Fan, Tian Shuo, Zhang Li, Zhang Tian-tai, Du Guan-hua
Publicado em 2012-09-01

Pinocembrin protects against β-amyloid-induced toxicity in neurons through inhibiting receptor for advanced glycation end products (RAGE)-independent signaling pathways and regulat...

Por Liu, Rui, Wu, Cai-xia, Zhou, Dan, Yang, Fan, Tian, Shuo, Zhang, Li, Zhang, Tian-tai, Du, Guan-hua
Publicado em 2012

Tyrosine sulfation in N-terminal domain of human C5a receptor is necessary for binding of chemotaxis inhibitory protein of Staphylococcus aureus

Por Liu, Zhen-jia, Yang, Yan-juan, Jiang, Lei, Xu, Ying-chun, Wang, Ai-xia, Du, Guan-hua, Gao, Jin-ming
Publicado em 2011

Inhibition of acetylcholinesterase by two genistein derivatives: kinetic analysis, molecular docking and molecular dynamics simulation

Por Fang, Jiansong, Wu, Ping, Yang, Ranyao, Gao, Li, Li, Chao, Wang, Dongmei, Wu, Song, Liu, Ai-Lin, Du, Guan-Hua
Publicado no Acta Pharm Sin B (2014)

Discovery, screening and evaluation of a plasma biomarker panel for subjects with psychological suboptimal health state using (1)H-NMR-based metabolomics profiles

Por Tian, Jun-sheng, Xia, Xiao-tao, Wu, Yan-fei, Zhao, Lei, Xiang, Huan, Du, Guan-hua, Zhang, Xiang, Qin, Xue-mei
Publicado no Sci Rep (2016)

DL0805-2, a novel indazole derivative, relaxes angiotensin II-induced contractions of rat aortic rings by inhibiting Rho kinase and calcium fluxes

Por Yuan, Tian-yi, Chen, Yu-cai, Zhang, Hui-fang, Li, Li, Jiao, Xiao-zhen, Xie, Ping, Fang, Lian-hua, Du, Guan-hua
Publicado no Acta Pharmacol Sin (2016)

AlzhCPI: A knowledge base for predicting chemical-protein interactions towards Alzheimer’s disease

Por Fang, Jiansong, Wang, Ling, Li, Yecheng, Lian, Wenwen, Pang, Xiaocong, Wang, Hong, Yuan, Dongsheng, Wang, Qi, Liu, Ai-Lin, Du, Guan-Hua
Publicado no PLoS One (2017)

Pinocembrin Protects Human Brain Microvascular Endothelial Cells against Fibrillar Amyloid-β (1−40)Injury by Suppressing the MAPK/NF-κB Inflammatory Pathways

Por Liu, Rui, Li, Jin-ze, Song, Jun-ke, Sun, Jia-lin, Li, Yong-jie, Zhou, Si-bai, Zhang, Tian-tai, Du, Guan-hua
Publicado em 2014

Preclinical Studies of the Potent and Selective Nicotinic α4β2 Receptor Ligand VMY-2-95

Por Kong, Hyesik, Song, Jun-ke, Yenugonda, Venkata Mahidhar, Zhang, Li, Shuo, Tian, Cheema, Amrita K., Kong, Yali, Du, Guan-hua, Brown, Milton L.
Publicado no Mol Pharm (2014)

DL0410, a novel dual cholinesterase inhibitor, protects mouse brains against Aβ-induced neuronal damage via the Akt/JNK signaling pathway

Por Zhou, Dan, Zhou, Wei, Song, Jun-ke, Feng, Zhang-ying, Yang, Ran-yao, Wu, Song, Wang, Lin, Liu, Ai-lin, Du, Guan-hua
Publicado no Acta Pharmacol Sin (2016)