Of mice and men: what rodent models don't tell us

Por Drake, Adam C
Publicado em 2013

Virus-specific host miRNAs: antiviral defenses or promoters of persistent infection?

Por Mahajan, Vinay S., Drake, Adam, Chen, Jianzhu
Publicado em 2008

Engineering humanized mice for improved hematopoietic reconstitution

Por Drake, Adam C, Chen, Qingfeng, Chen, Jianzhu
Publicado em 2012

TP53 engagement with the genome occurs in distinct local chromatin environments via pioneer factor activity

Por Sammons, Morgan A., Zhu, Jiajun, Drake, Adam M., Berger, Shelley L.
Publicado no Genome Res (2015)

Persistence of tumor-infiltrating CD8 T cells is tumor-dependent but antigen-independent

Por Olurinde, Mobolaji O, Shen, Ching-Hung, Drake, Adam, Bai, Ailin, Chen, Jianzhu
Publicado em 2011

Interleukins 7 and 15 Maintain Human T Cell Proliferative Capacity through STAT5 Signaling

Por Drake, Adam, Kaur, Mandeep, Iliopoulou, Bettina P., Phennicie, Ryan, Hanson, Amanda, Chen, Jianzhu
Publicado no PLoS One (2016)

ACETYL-COA SYNTHETASE REGULATES HISTONE ACETYLATION AND HIPPOCAMPAL MEMORY

Por Mews, Philipp, Donahue, Greg, Drake, Adam M., Luczak, Vincent, Abel, Ted, Berger, Shelley L.
Publicado no Nature (2017)

Koch Institute Symposium on Cancer Immunology and Immunotherapy

Por Drake, Adam, Joshi, Nikhil S., Szeto, Gregory L, Zhu, Eric, Eisen, Herman N., Irvine, Darrell J.
Publicado em 2013

Human CD34(+) CD133(+) Hematopoietic Stem Cells Cultured with Growth Factors Including Angptl5 Efficiently Engraft Adult NOD-SCID Il2rγ(−/−) (NSG) Mice

Por Drake, Adam C., Khoury, Maroun, Leskov, Ilya, Iliopoulou, Bettina P., Fragoso, Maria, Lodish, Harvey, Chen, Jianzhu
Publicado em 2011

Graphene Multilayers as Gates for Multi-Week Sequential Release of Proteins from Surfaces

Por Hong, Jinkee, Shah, Nisarg J., Drake, Adam C., DeMuth, Peter C., Lee, Jong Bum, Chen, Jianzhu, Hammond, Paula T.
Publicado em 2011

Induction and Therapeutic Targeting of Human NPM1c(+) Myeloid Leukemia in the Presence of Autologous Immune System in Mice

Por Kaur, Mandeep, Drake, Adam C., Hu, Guangan, Rudnick, Stephen, Chen, Qingfeng, Phennicie, Ryan, Attar, Ricardo, Nemeth, Jeffrey, Gaudet, Francois, Chen, Jianzhu
Publicado no J Immunol (2019)

Mesenchymal Stem Cells Secreting Angiopoietin-Like-5 Support Efficient Expansion of Human Hematopoietic Stem Cells Without Compromising Their Repopulating Potential

Por Khoury, Maroun, Drake, Adam, Chen, Qingfeng, Dong, Di, Leskov, Ilya, Fragoso, Maria F., Li, Yan, Iliopoulou, Bettina P., Hwang, William, Lodish, Harvey F., Chen, Jianzhu
Publicado em 2011

Rapid generation of human B-cell lymphomas via combined expression of Myc and Bcl2 and their use as a preclinical model for biological therapies

Por Leskov, Ilya, Pallasch, Christian P., Drake, Adam, Iliopoulou, Bettina P., Souza, Amanda, Shen, Ching-Hung, Schweighofer, Carmen D., Abruzzo, Lynne, Frenzel, Lukas P., Wendtner, Clemens M., Hemann, Michael T., Chen, Jianzhu
Publicado em 2012

MLL1 is essential for the senescence-associated secretory phenotype

Por Capell, Brian C., Drake, Adam M., Zhu, Jiajun, Shah, Parisha P., Dou, Zhixun, Dorsey, Jean, Simola, Daniel F., Donahue, Greg, Sammons, Morgan, Rai, Taranjit Singh, Natale, Christopher, Ridky, Todd W., Adams, Peter D., Berger, Shelley L.
Publicado no Genes Dev (2016)

Sensitizing Protective Tumor Microenvironments to Antibody-Mediated Therapy

Por Pallasch, Christian P., Leskov, Ilya, Braun, Christian J., Vorholt, Daniela, Drake, Adam, Soto-Feliciano, Yadira M., Bent, Eric H., Schwamb, Janine, Iliopoulou, Bettina, Kutsch, Nadine, van Rooijen, Nico, Frenzel, Lukas P., Wendtner, Clemens M., Heukamp, Lukas, Kreuzer, Karl Anton, Hallek, Michael, Chen, Jianzhu, Hemann, Michael T.
Publicado em 2014

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

Por Pauken, Kristen E., Sammons, Morgan A., Odorizzi, Pamela M., Manne, Sasikanth, Godec, Jernej, Khan, Omar, Drake, Adam M., Chen, Zeyu, Sen, Debattama R., Kurachi, Makoto, Barnitz, R. Anthony, Bartman, Caroline, Bengsch, Bertram, Huang, Alexander C., Schenkel, Jason M., Vahedi, Golnaz, Haining, W. Nicholas, Berger, Shelley L., Wherry, E. John
Publicado no Science (2016)

Autophagy mediates degradation of nuclear lamina

Por Dou, Zhixun, Xu, Caiyue, Donahue, Greg, Shimi, Takeshi, Pan, Ji-An, Zhu, Jiajun, Ivanov, Andrejs, Capell, Brian C., Drake, Adam M., Shah, Parisha P., Catanzaro, Joseph M., Ricketts, M. Daniel, Lamark, Trond, Adam, Stephen A., Marmorstein, Ronen, Zong, Wei-Xing, Johansen, Terje, Goldman, Robert D., Adams, Peter D., Berger, Shelley L.
Publicado no Nature (2015)

Densely interconnected transcriptional circuits control cell states in human hematopoiesis

Por Novershtern, Noa, Subramanian, Aravind, Lawton, Lee N., Mak, Raymond H., Haining, W. Nicholas, McConkey, Marie E., Habib, Naomi, Yosef, Nir, Chang, Cindy Y., Shay, Tal, Frampton, Garrett M., Drake, Adam C. B., Leskov, Ilya, Nilsson, Bjorn, Preffer, Fred, Dombkowski, David, Evans, John W., Liefeld, Ted, Smutko, John S., Chen, Jianzhu, Friedman, Nir, Young, Richard A., Golub, Todd R., Regev, Aviv, Ebert, Benjamin L.
Publicado em 2011

Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA

Por Wan, Nathan, Weinberg, David, Liu, Tzu-Yu, Niehaus, Katherine, Ariazi, Eric A., Delubac, Daniel, Kannan, Ajay, White, Brandon, Bailey, Mitch, Bertin, Marvin, Boley, Nathan, Bowen, Derek, Cregg, James, Drake, Adam M., Ennis, Riley, Fransen, Signe, Gafni, Erik, Hansen, Loren, Liu, Yaping, Otte, Gabriel L., Pecson, Jennifer, Rice, Brandon, Sanderson, Gabriel E., Sharma, Aarushi, St. John, John, Tang, Catherina, Tzou, Abraham, Young, Leilani, Putcha, Girish, Haque, Imran S.
Publicado no BMC Cancer (2019)