Sending proteins to dense core secretory granules: still a lot to sort out

Por Dikeakos, Jimmy D., Reudelhuber, Timothy L.
Publicado em 2007

HIV-I Nef inhibitors: a novel class of HIV-specific immune adjuvants in support of a cure

Por Dekaban, Gregory A., Dikeakos, Jimmy D.
Publicado no AIDS Res Ther (2017)

Visualizing Interactions Between HIV-1 Nef and Host Cellular Proteins Using Ground-State Depletion Microscopy

Por Dirk, Brennan S., Heit, Bryan, Dikeakos, Jimmy D.
Publicado no AIDS Res Hum Retroviruses (2015)

Where in the Cell Are You? Probing HIV-1 Host Interactions through Advanced Imaging Techniques

Por Dirk, Brennan S., Van Nynatten, Logan R., Dikeakos, Jimmy D.
Publicado no Viruses (2016)

An interdomain binding site on HIV-1 Nef interacts with PACS-1 and PACS-2 on endosomes to down-regulate MHC-I

Por Dikeakos, Jimmy D., Thomas, Laurel, Kwon, Grace, Elferich, Johannes, Shinde, Ujwal, Thomas, Gary
Publicado em 2012

The HIV-1 accessory proteins Nef and Vpu downregulate total and cell surface CD28 in CD4(+) T cells

Por Pawlak, Emily N., Dirk, Brennan S., Jacob, Rajesh Abraham, Johnson, Aaron L., Dikeakos, Jimmy D.
Publicado no Retrovirology (2018)

Functional and Structural Mimicry of Cellular Protein Kinase A Anchoring Proteins by a Viral Oncoprotein

Por King, Cason R., Cohen, Michael J., Fonseca, Gregory J., Dirk, Brennan S., Dikeakos, Jimmy D., Mymryk, Joe S.
Publicado no PLoS Pathog (2016)

A Highly Conserved Residue in HIV-1 Nef Alpha Helix 2 Modulates Protein Expression

Por Johnson, Aaron L., Dirk, Brennan S., Coutu, Mathieu, Haeryfar, S. M. Mansour, Arts, Eric J., Finzi, Andrés, Dikeakos, Jimmy D.
Publicado no mSphere (2016)

Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease

Por Dikeakos, Jimmy D., Di Lello, Paola, Lacombe, Marie-Josée, Ghirlando, Rodolfo, Legault, Pascale, Reudelhuber, Timothy L., Omichinski, James G.
Publicado em 2009

Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Protein-induced Lysosomal Translocation of Proapoptotic Effectors Is Mediated by Phosphofurin Acidic Cluster Sorting...

Por Werneburg, Nathan W., Bronk, Steve F., Guicciardi, Maria Eugenia, Thomas, Laurel, Dikeakos, Jimmy D., Thomas, Gary, Gores, Gregory J.
Publicado em 2012

HIV-1 Nef sequesters MHC-I intracellularly by targeting early stages of endocytosis and recycling

Por Dirk, Brennan S., Pawlak, Emily N., Johnson, Aaron L., Van Nynatten, Logan R., Jacob, Rajesh A., Heit, Bryan, Dikeakos, Jimmy D.
Publicado no Sci Rep (2016)

Identification of Novel Subcellular Localization and Trafficking of HIV-1 Nef Variants from Reference Strains G (F1.93.HH8793) and H (BE.93.VI997)

Por Van Nynatten, Logan R., Johnson, Aaron L., Dirk, Brennan S., Pawlak, Emily N., Jacob, Rajesh Abraham, Haeryfar, S. M. Mansour, Dikeakos, Jimmy D.
Publicado no Viruses (2018)

Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin

Por Khadir, Fatemeh, Shaler, Christopher R., Oryan, Ahmad, Rudak, Patrick T., Mazzuca, Delfina M., Taheri, Tahereh, Dikeakos, Jimmy D., Haeryfar, S. M. Mansour, Rafati, Sima
Publicado no PLoS Negl Trop Dis (2018)

Viral Bimolecular Fluorescence Complementation: A Novel Tool to Study Intracellular Vesicular Trafficking Pathways

Por Dirk, Brennan S., Jacob, Rajesh Abraham, Johnson, Aaron L., Pawlak, Emily N., Cavanagh, P. Craig, Van Nynatten, Logan, Haeryfar, S. M. Mansour, Dikeakos, Jimmy D.
Publicado no PLoS One (2015)

Interferon-induced HERC5 is evolving under positive selection and inhibits HIV-1 particle production by a novel mechanism targeting Rev/RRE-dependent RNA nuclear export

Por Woods, Matthew William, Tong, Jessica Gayle, Tom, Sean Kevin, Szabo, Peter Anthony, Cavanagh, Peter Craig, Dikeakos, Jimmy Dimitrios, Haeryfar, SM Mansour, Barr, Stephen Dominic
Publicado em 2014

Antagonistic Coevolution of MER Tyrosine Kinase Expression and Function

Por Evans, Amanda L., Blackburn, Jack W.D., Taruc, Kyle, Kipp, Angela, Dirk, Brennan S., Hunt, Nina R., Barr, Stephen D., Dikeakos, Jimmy D., Heit, Bryan
Publicado no Mol Biol Evol (2017)

Bacterial Superantigens Expand and Activate, Rather than Delete or Incapacitate, Preexisting Antigen-Specific Memory CD8(+) T Cells

Por Meilleur, Courtney E, Wardell, Christine M, Mele, Tina S, Dikeakos, Jimmy D, Bennink, Jack R, Mu, Hong-Hua, McCormick, John K, Haeryfar, S M Mansour
Publicado no J Infect Dis (2019)

The multi-functional sorting protein PACS-2 regulates SIRT1-mediated deacetylation of p53 to modulate p21-dependent cell cycle arrest

Por Atkins, Katelyn M., Thomas, Laura L., Barroso-González, Jonathan, Thomas, Laurel, Auclair, Sylvain, Yin, Jun, Kang, Hyeog, Chung, Jay H., Dikeakos, Jimmy D., Thomas, Gary
Publicado no Cell Rep (2014)

MIiSR: Molecular Interactions in Super-Resolution Imaging Enables the Analysis of Protein Interactions, Dynamics and Formation of Multi-protein Structures

Por Caetano, Fabiana A., Dirk, Brennan S., Tam, Joshua H. K., Cavanagh, P. Craig, Goiko, Maria, Ferguson, Stephen S. G., Pasternak, Stephen H., Dikeakos, Jimmy D., de Bruyn, John R., Heit, Bryan
Publicado no PLoS Comput Biol (2015)

Pathogenic infection of Rhesus macaques by an evolving SIV-HIV derived from CCR5-using envelope genes of acute HIV-1 infections

Por Asmal, Mohammed, Lane, Sophie, Tian, Meijuan, Nickle, Gabrielle, Venner, Colin, Dirk, Brennan, Dikeakos, Jimmy, Luedemann, Corinne, Mach, Linh, Balachandran, Harikrishnan, Buzby, Adam, Rao, Srinivas, Letvin, Norman, Gao, Yong, Arts, Eric J.
Publicado no Virology (2016)